ETV7.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV7.H12CORE.0.SM.B
Gene (human)	ETV7 (GeneCards)
Gene synonyms (human)	TEL2, TELB, TREF
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	ddMSSGGAAGYRhhdvbbn
GC content	53.93%
Information content (bits; total / per base)	14.89 / 0.784
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9974

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.637	0.652	0.479	0.499	0.611	0.627	1.463	1.551	2.125	6.509

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.972	0.967	0.892	0.894	0.816	0.83
Overall, 2 experiments	best	1.0	1.0	0.999	0.998	0.988	0.986
Methyl HT-SELEX, 1 experiments	median	0.945	0.935	0.786	0.789	0.644	0.674
Methyl HT-SELEX, 1 experiments	best	0.945	0.935	0.786	0.789	0.644	0.674
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.999	0.998	0.988	0.986
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.999	0.998	0.988	0.986

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.785	0.409	0.709	0.401

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.2
HGNC	HGNC:18160
MGI
EntrezGene (human)	GeneID:51513 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ETV7_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9Y603 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ETV7.H12CORE.0.SM.B.pcm
PWM	ETV7.H12CORE.0.SM.B.pwm
PFM	ETV7.H12CORE.0.SM.B.pfm
Alignment	ETV7.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	ETV7.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	ETV7.H12CORE.0.SM.B_jaspar_format.txt
MEME format	ETV7.H12CORE.0.SM.B_meme_format.meme
Transfac format	ETV7.H12CORE.0.SM.B_transfac_format.txt
Homer format	ETV7.H12CORE.0.SM.B_homer_format_0.001.txt ETV7.H12CORE.0.SM.B_homer_format_0.0005.txt ETV7.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2004.75	1432.75	1566.75	4969.75
02	2561.25	904.25	1161.25	5347.25
03	1626.0	6347.0	878.0	1123.0
04	706.0	7762.0	1307.0	199.0
05	865.0	6765.0	2160.0	184.0
06	6.0	0.0	9968.0	0.0
07	0.0	1.0	9973.0	0.0
08	9951.0	0.0	0.0	23.0
09	9836.0	26.0	2.0	110.0
10	2028.0	116.0	7809.0	21.0
11	350.0	1929.0	146.0	7549.0
12	5596.0	457.0	3161.0	760.0
13	1741.0	4742.0	1357.0	2134.0
14	1657.0	1441.0	1420.0	5456.0
15	1451.0	1450.0	1552.0	5521.0
16	1311.0	6051.0	1353.0	1259.0
17	1133.0	5657.0	1977.0	1207.0
18	1608.5	1795.5	4147.5	2422.5
19	2564.0	2623.0	2767.0	2020.0

PFM

	A	C	G	T
01	0.201	0.144	0.157	0.498
02	0.257	0.091	0.116	0.536
03	0.163	0.636	0.088	0.113
04	0.071	0.778	0.131	0.02
05	0.087	0.678	0.217	0.018
06	0.001	0.0	0.999	0.0
07	0.0	0.0	1.0	0.0
08	0.998	0.0	0.0	0.002
09	0.986	0.003	0.0	0.011
10	0.203	0.012	0.783	0.002
11	0.035	0.193	0.015	0.757
12	0.561	0.046	0.317	0.076
13	0.175	0.475	0.136	0.214
14	0.166	0.144	0.142	0.547
15	0.145	0.145	0.156	0.554
16	0.131	0.607	0.136	0.126
17	0.114	0.567	0.198	0.121
18	0.161	0.18	0.416	0.243
19	0.257	0.263	0.277	0.203

PWM

	A	C	G	T
01	-0.218	-0.553	-0.464	0.689
02	0.027	-1.013	-0.763	0.762
03	-0.427	0.934	-1.042	-0.797
04	-1.259	1.135	-0.645	-2.518
05	-1.057	0.997	-0.143	-2.595
06	-5.706	-6.989	1.385	-6.989
07	-6.989	-6.628	1.386	-6.989
08	1.383	-6.989	-6.989	-4.591
09	1.372	-4.479	-6.363	-3.101
10	-0.206	-3.049	1.141	-4.674
11	-1.958	-0.256	-2.823	1.107
12	0.808	-1.693	0.237	-1.186
13	-0.359	0.642	-0.608	-0.156
14	-0.408	-0.548	-0.562	0.783
15	-0.541	-0.541	-0.474	0.794
16	-0.642	0.886	-0.611	-0.682
17	-0.788	0.819	-0.232	-0.725
18	-0.438	-0.328	0.508	-0.029
19	0.028	0.051	0.104	-0.21

Standard thresholds

P-value	Threshold
0.001	2.36281
0.0005	3.85736
0.0001	6.67936