MotifETV6.H12INVIVO.0.PS.A
Gene (human)ETV6
(GeneCards)
Gene synonyms (human)TEL, TEL1
Gene (mouse)Etv6
Gene synonyms (mouse)Tel, Tel1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length10
ConsensusvSMGGAAGYR
GC content61.71%
Information content (bits; total / per base)11.579 / 1.158
Data sourcesChIP-Seq + HT-SELEX
Aligned words997

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.883 0.924 0.781 0.822 0.847 0.908 2.701 3.286 142.161 193.066
Mouse 4 (25) 0.842 0.919 0.791 0.891 0.85 0.906 3.565 4.174 108.509 326.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.79 0.768 0.653 0.656 0.575 0.592
best 0.856 0.836 0.693 0.698 0.595 0.617
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETV6-like {3.5.2.6} (TFClass)
TFClass IDTFClass: 3.5.2.6.1
HGNCHGNC:3495
MGIMGI:109336
EntrezGene (human)GeneID:2120
(SSTAR profile)
EntrezGene (mouse)GeneID:14011
(SSTAR profile)
UniProt ID (human)ETV6_HUMAN
UniProt ID (mouse)ETV6_MOUSE
UniProt AC (human)P41212
(TFClass)
UniProt AC (mouse)P97360
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01369.0165.0400.063.0
02105.0601.0273.018.0
03224.0725.033.015.0
0412.00.0977.08.0
0511.08.0971.07.0
06979.015.00.03.0
07972.02.013.010.0
08100.019.0875.03.0
0993.0216.068.0620.0
10132.0102.0689.074.0
PFM
ACGT
010.370.1650.4010.063
020.1050.6030.2740.018
030.2250.7270.0330.015
040.0120.00.980.008
050.0110.0080.9740.007
060.9820.0150.00.003
070.9750.0020.0130.01
080.10.0190.8780.003
090.0930.2170.0680.622
100.1320.1020.6910.074
PWM
ACGT
010.39-0.4090.47-1.355
02-0.8550.8760.09-2.543
03-0.1061.063-1.978-2.708
04-2.906-4.9791.361-3.251
05-2.982-3.2511.355-3.359
061.363-2.708-4.979-3.972
071.356-4.21-2.836-3.064
08-0.903-2.4941.251-3.972
09-0.974-0.142-1.2810.907
10-0.63-0.8841.012-1.198
Standard thresholds
P-value Threshold
0.001 4.201985
0.0005 5.26237
0.0001 7.346905