ETV6.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV6.H12INVITRO.1.P.B
Gene (human)	ETV6 (GeneCards)
Gene synonyms (human)	TEL, TEL1
Gene (mouse)	Etv6
Gene synonyms (mouse)	Tel, Tel1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	dvSMGGAAGKRv
GC content	52.64%
Information content (bits; total / per base)	12.186 / 1.016
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (35)	0.877	0.901	0.761	0.808	0.899	0.93	3.461	3.938	134.824	171.036
Mouse	4 (25)	0.746	0.848	0.622	0.739	0.778	0.849	2.491	2.922	50.237	193.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.767	0.733	0.639	0.636	0.567	0.58
Non-Methyl HT-SELEX, 2 experiments	best	0.826	0.791	0.676	0.674	0.585	0.603

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.1
HGNC	HGNC:3495
MGI	MGI:109336
EntrezGene (human)	GeneID:2120 (SSTAR profile)
EntrezGene (mouse)	GeneID:14011 (SSTAR profile)
UniProt ID (human)	ETV6_HUMAN
UniProt ID (mouse)	ETV6_MOUSE
UniProt AC (human)	P41212 (TFClass)
UniProt AC (mouse)	P97360 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	ETV6.H12INVITRO.1.P.B.pcm
PWM	ETV6.H12INVITRO.1.P.B.pwm
PFM	ETV6.H12INVITRO.1.P.B.pfm
Alignment	ETV6.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	ETV6.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	ETV6.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	ETV6.H12INVITRO.1.P.B_meme_format.meme
Transfac format	ETV6.H12INVITRO.1.P.B_transfac_format.txt
Homer format	ETV6.H12INVITRO.1.P.B_homer_format_0.001.txt ETV6.H12INVITRO.1.P.B_homer_format_0.0005.txt ETV6.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	541.0	54.0	258.0	147.0
02	455.0	150.0	337.0	58.0
03	137.0	387.0	454.0	22.0
04	678.0	227.0	86.0	9.0
05	2.0	2.0	993.0	3.0
06	1.0	1.0	996.0	2.0
07	991.0	4.0	4.0	1.0
08	988.0	1.0	6.0	5.0
09	133.0	5.0	859.0	3.0
10	101.0	129.0	144.0	626.0
11	269.0	53.0	599.0	79.0
12	346.0	138.0	430.0	86.0

PFM

	A	C	G	T
01	0.541	0.054	0.258	0.147
02	0.455	0.15	0.337	0.058
03	0.137	0.387	0.454	0.022
04	0.678	0.227	0.086	0.009
05	0.002	0.002	0.993	0.003
06	0.001	0.001	0.996	0.002
07	0.991	0.004	0.004	0.001
08	0.988	0.001	0.006	0.005
09	0.133	0.005	0.859	0.003
10	0.101	0.129	0.144	0.626
11	0.269	0.053	0.599	0.079
12	0.346	0.138	0.43	0.086

PWM

	A	C	G	T
01	0.768	-1.508	0.031	-0.526
02	0.596	-0.506	0.297	-1.439
03	-0.596	0.435	0.594	-2.362
04	0.993	-0.096	-1.054	-3.156
05	-4.213	-4.213	1.374	-3.975
06	-4.525	-4.525	1.377	-4.213
07	1.372	-3.783	-3.783	-4.525
08	1.369	-4.525	-3.484	-3.622
09	-0.625	-3.622	1.229	-3.975
10	-0.896	-0.655	-0.547	0.914
11	0.073	-1.526	0.87	-1.137
12	0.323	-0.589	0.539	-1.054

Standard thresholds

P-value	Threshold
0.001	3.83292
0.0005	5.063515
0.0001	7.42721