MotifETV6.H12INVITRO.0.PS.A
Gene (human)ETV6
(GeneCards)
Gene synonyms (human)TEL, TEL1
Gene (mouse)Etv6
Gene synonyms (mouse)Tel, Tel1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length10
ConsensusvSCGGAAGYR
GC content60.97%
Information content (bits; total / per base)12.356 / 1.236
Data sourcesChIP-Seq + HT-SELEX
Aligned words990

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.879 0.918 0.771 0.816 0.825 0.885 2.495 3.088 142.009 195.523
Mouse 4 (25) 0.834 0.93 0.79 0.906 0.842 0.916 3.612 4.372 114.398 342.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.792 0.774 0.653 0.658 0.577 0.594
best 0.859 0.844 0.694 0.702 0.597 0.619
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETV6-like {3.5.2.6} (TFClass)
TFClass IDTFClass: 3.5.2.6.1
HGNCHGNC:3495
MGIMGI:109336
EntrezGene (human)GeneID:2120
(SSTAR profile)
EntrezGene (mouse)GeneID:14011
(SSTAR profile)
UniProt ID (human)ETV6_HUMAN
UniProt ID (mouse)ETV6_MOUSE
UniProt AC (human)P41212
(TFClass)
UniProt AC (mouse)P97360
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01443.0207.0280.060.0
0287.0730.0163.010.0
03122.0847.010.011.0
0411.02.0964.013.0
0511.013.0964.02.0
06987.02.00.01.0
07974.02.06.08.0
08109.027.0853.01.0
0948.0230.030.0682.0
10165.096.0610.0119.0
PFM
ACGT
010.4470.2090.2830.061
020.0880.7370.1650.01
030.1230.8560.010.011
040.0110.0020.9740.013
050.0110.0130.9740.002
060.9970.0020.00.001
070.9840.0020.0060.008
080.110.0270.8620.001
090.0480.2320.030.689
100.1670.0970.6160.12
PWM
ACGT
010.579-0.1770.123-1.396
02-1.0331.077-0.414-3.057
03-0.71.225-3.057-2.975
04-2.975-4.2031.355-2.829
05-2.975-2.8291.355-4.203
061.378-4.203-4.973-4.516
071.365-4.203-3.474-3.244
08-0.811-2.1611.232-4.516
09-1.612-0.073-2.0611.009
10-0.402-0.9360.898-0.725
Standard thresholds
P-value Threshold
0.001 3.85966
0.0005 4.990905
0.0001 7.288155