ETV5.H12CORE.1.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV5.H12CORE.1.PM.A
Gene (human)	ETV5 (GeneCards)
Gene synonyms (human)	ERM
Gene (mouse)	Etv5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	13
Consensus	vvdCMGGAAGYvv
GC content	58.73%
Information content (bits; total / per base)	10.915 / 0.84
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	982

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.673	0.901	0.517	0.809	0.67	0.896	1.752	3.432	7.307	292.699
Mouse	4 (20)	0.732	0.812	0.697	0.791	0.732	0.807	2.869	3.502	58.729	115.092

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.994	0.989	0.986	0.98	0.93	0.926
Overall, 4 experiments	best	0.997	0.995	0.994	0.991	0.987	0.981
Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.994	0.991	0.987	0.981
Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.994	0.991	0.987	0.981
Non-Methyl HT-SELEX, 3 experiments	median	0.993	0.989	0.983	0.976	0.88	0.882
Non-Methyl HT-SELEX, 3 experiments	best	0.994	0.989	0.99	0.983	0.98	0.971

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.948	0.853	0.93	0.567
batch 2	0.924	0.753	0.873	0.599

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELK-like {3.5.2.2} (TFClass)
TFClass ID	TFClass: 3.5.2.2.6
HGNC	HGNC:3494
MGI	MGI:1096867
EntrezGene (human)	GeneID:2119 (SSTAR profile)
EntrezGene (mouse)	GeneID:104156 (SSTAR profile)
UniProt ID (human)	ETV5_HUMAN
UniProt ID (mouse)	ETV5_MOUSE
UniProt AC (human)	P41161 (TFClass)
UniProt AC (mouse)	Q9CXC9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 4 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ETV5.H12CORE.1.PM.A.pcm
PWM	ETV5.H12CORE.1.PM.A.pwm
PFM	ETV5.H12CORE.1.PM.A.pfm
Alignment	ETV5.H12CORE.1.PM.A.words.tsv
Threshold to P-value map	ETV5.H12CORE.1.PM.A.thr
Motif in other formats
JASPAR format	ETV5.H12CORE.1.PM.A_jaspar_format.txt
MEME format	ETV5.H12CORE.1.PM.A_meme_format.meme
Transfac format	ETV5.H12CORE.1.PM.A_transfac_format.txt
Homer format	ETV5.H12CORE.1.PM.A_homer_format_0.001.txt ETV5.H12CORE.1.PM.A_homer_format_0.0005.txt ETV5.H12CORE.1.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	304.0	221.0	330.0	127.0
02	232.0	207.0	404.0	139.0
03	408.0	120.0	333.0	121.0
04	45.0	790.0	133.0	14.0
05	304.0	652.0	10.0	16.0
06	32.0	1.0	895.0	54.0
07	24.0	3.0	952.0	3.0
08	971.0	3.0	2.0	6.0
09	907.0	3.0	17.0	55.0
10	205.0	25.0	740.0	12.0
11	65.0	268.0	99.0	550.0
12	200.0	144.0	521.0	117.0
13	251.0	212.0	412.0	107.0

PFM

	A	C	G	T
01	0.31	0.225	0.336	0.129
02	0.236	0.211	0.411	0.142
03	0.415	0.122	0.339	0.123
04	0.046	0.804	0.135	0.014
05	0.31	0.664	0.01	0.016
06	0.033	0.001	0.911	0.055
07	0.024	0.003	0.969	0.003
08	0.989	0.003	0.002	0.006
09	0.924	0.003	0.017	0.056
10	0.209	0.025	0.754	0.012
11	0.066	0.273	0.101	0.56
12	0.204	0.147	0.531	0.119
13	0.256	0.216	0.42	0.109

PWM

	A	C	G	T
01	0.212	-0.104	0.294	-0.653
02	-0.056	-0.169	0.495	-0.563
03	0.505	-0.709	0.303	-0.7
04	-1.666	1.164	-0.607	-2.755
05	0.212	0.972	-3.049	-2.635
06	-1.992	-4.509	1.288	-1.49
07	-2.263	-3.958	1.35	-3.958
08	1.37	-3.958	-4.196	-3.466
09	1.302	-3.958	-2.581	-1.472
10	-0.179	-2.225	1.099	-2.891
11	-1.31	0.087	-0.898	0.803
12	-0.203	-0.529	0.749	-0.734
13	0.022	-0.146	0.515	-0.821

Standard thresholds

P-value	Threshold
0.001	4.50371
0.0005	5.45431
0.0001	7.381415