ETV5.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV5.H12CORE.0.PS.A
Gene (human)	ETV5 (GeneCards)
Gene synonyms (human)	ERM
Gene (mouse)	Etv5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	ndSCGGAWGYn
GC content	58.39%
Information content (bits; total / per base)	11.407 / 1.037
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9949

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.689	0.93	0.534	0.862	0.6	0.875	1.351	2.948	11.199	384.432
Mouse	4 (20)	0.734	0.814	0.703	0.799	0.69	0.778	2.546	3.2	71.745	139.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.996	0.992	0.991	0.987	0.943	0.941
Overall, 4 experiments	best	0.998	0.996	0.995	0.992	0.989	0.984
Methyl HT-SELEX, 1 experiments	median	0.998	0.996	0.995	0.992	0.985	0.98
Methyl HT-SELEX, 1 experiments	best	0.998	0.996	0.995	0.992	0.985	0.98
Non-Methyl HT-SELEX, 3 experiments	median	0.996	0.992	0.988	0.983	0.9	0.902
Non-Methyl HT-SELEX, 3 experiments	best	0.996	0.993	0.994	0.99	0.989	0.984

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.956	0.905	0.963	0.724
batch 2	0.953	0.855	0.931	0.717

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELK-like {3.5.2.2} (TFClass)
TFClass ID	TFClass: 3.5.2.2.6
HGNC	HGNC:3494
MGI	MGI:1096867
EntrezGene (human)	GeneID:2119 (SSTAR profile)
EntrezGene (mouse)	GeneID:104156 (SSTAR profile)
UniProt ID (human)	ETV5_HUMAN
UniProt ID (mouse)	ETV5_MOUSE
UniProt AC (human)	P41161 (TFClass)
UniProt AC (mouse)	Q9CXC9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 4 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ETV5.H12CORE.0.PS.A.pcm
PWM	ETV5.H12CORE.0.PS.A.pwm
PFM	ETV5.H12CORE.0.PS.A.pfm
Alignment	ETV5.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	ETV5.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	ETV5.H12CORE.0.PS.A_jaspar_format.txt
MEME format	ETV5.H12CORE.0.PS.A_meme_format.meme
Transfac format	ETV5.H12CORE.0.PS.A_transfac_format.txt
Homer format	ETV5.H12CORE.0.PS.A_homer_format_0.001.txt ETV5.H12CORE.0.PS.A_homer_format_0.0005.txt ETV5.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2167.75	2389.75	2787.75	2603.75
02	4474.25	566.25	2371.25	2537.25
03	546.0	7365.0	1796.0	242.0
04	395.0	9512.0	23.0	19.0
05	1.0	0.0	9944.0	4.0
06	0.0	0.0	9936.0	13.0
07	9930.0	10.0	0.0	9.0
08	6476.0	98.0	25.0	3350.0
09	1232.0	536.0	8090.0	91.0
10	647.0	3041.0	712.0	5549.0
11	2951.75	1536.75	3164.75	2295.75

PFM

	A	C	G	T
01	0.218	0.24	0.28	0.262
02	0.45	0.057	0.238	0.255
03	0.055	0.74	0.181	0.024
04	0.04	0.956	0.002	0.002
05	0.0	0.0	0.999	0.0
06	0.0	0.0	0.999	0.001
07	0.998	0.001	0.0	0.001
08	0.651	0.01	0.003	0.337
09	0.124	0.054	0.813	0.009
10	0.065	0.306	0.072	0.558
11	0.297	0.154	0.318	0.231

PWM

	A	C	G	T
01	-0.137	-0.04	0.114	0.046
02	0.587	-1.477	-0.048	0.02
03	-1.513	1.085	-0.325	-2.321
04	-1.835	1.341	-4.589	-4.761
05	-6.626	-6.986	1.385	-5.979
06	-6.986	-6.986	1.384	-5.092
07	1.384	-5.31	-6.986	-5.395
08	0.956	-3.212	-4.513	0.298
09	-0.702	-1.531	1.179	-3.284
10	-1.344	0.201	-1.249	0.802
11	0.171	-0.481	0.241	-0.08

Standard thresholds

P-value	Threshold
0.001	4.11869
0.0005	5.445685
0.0001	7.60602