MotifETV4.H12INVITRO.1.SM.B
Gene (human)ETV4
(GeneCards)
Gene synonyms (human)E1AF, PEA3
Gene (mouse)Etv4
Gene synonyms (mouse)Pea-3, Pea3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusnnACCGGAAGTdn
GC content55.1%
Information content (bits; total / per base)15.689 / 1.207
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9786

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (24) 0.786 0.922 0.662 0.838 0.749 0.912 2.034 3.362 39.357 291.215

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.999 0.999 0.997 0.995 0.989 0.986
best 1.0 0.999 1.0 0.999 0.999 0.998
Methyl HT-SELEX, 3 experiments median 0.999 0.998 0.997 0.995 0.99 0.986
best 1.0 0.999 0.999 0.999 0.997 0.996
Non-Methyl HT-SELEX, 5 experiments median 0.999 0.999 0.996 0.995 0.928 0.922
best 1.0 0.999 1.0 0.999 0.999 0.998

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.834 0.547 0.705 0.47
batch 2 0.947 0.86 0.871 0.722
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyELK-like {3.5.2.2} (TFClass)
TFClass IDTFClass: 3.5.2.2.5
HGNCHGNC:3493
MGIMGI:99423
EntrezGene (human)GeneID:2118
(SSTAR profile)
EntrezGene (mouse)GeneID:18612
(SSTAR profile)
UniProt ID (human)ETV4_HUMAN
UniProt ID (mouse)ETV4_MOUSE
UniProt AC (human)P43268
(TFClass)
UniProt AC (mouse)P28322
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
012950.251983.252599.252253.25
022349.751955.753816.751663.75
037884.070.0890.0942.0
0488.09453.0235.010.0
05333.09453.00.00.0
060.00.09786.00.0
070.00.09786.00.0
089786.00.00.00.0
099417.01.00.0368.0
10394.053.09338.01.0
11113.01263.0253.08157.0
124398.5838.53360.51188.5
133369.52606.52360.51449.5
PFM
ACGT
010.3010.2030.2660.23
020.240.20.390.17
030.8060.0070.0910.096
040.0090.9660.0240.001
050.0340.9660.00.0
060.00.01.00.0
070.00.01.00.0
081.00.00.00.0
090.9620.00.00.038
100.040.0050.9540.0
110.0120.1290.0260.834
120.4490.0860.3430.121
130.3440.2660.2410.148
PWM
ACGT
010.187-0.210.061-0.082
02-0.04-0.2240.444-0.385
031.17-3.523-1.01-0.953
04-3.31.351-2.334-5.294
05-1.9881.351-6.972-6.972
06-6.972-6.9721.386-6.972
07-6.972-6.9721.386-6.972
081.386-6.972-6.972-6.972
091.347-6.61-6.972-1.889
10-1.821-3.7911.339-6.61
11-3.056-0.66-2.2611.204
120.586-1.0690.317-0.721
130.320.063-0.036-0.523
Standard thresholds
P-value Threshold
0.001 0.398965
0.0005 2.17876
0.0001 5.820235