MotifETV2.H12INVITRO.1.PM.A
Gene (human)ETV2
(GeneCards)
Gene synonyms (human)ER71, ETSRP71
Gene (mouse)Etv2
Gene synonyms (mouse)Er71, Etsrp71
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensusndRCAGGAARYdn
GC content49.3%
Information content (bits; total / per base)13.903 / 1.069
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words9239

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.94 0.943 0.869 0.874 0.94 0.942 3.842 3.852 220.906 240.678
Mouse 2 (13) 0.948 0.967 0.878 0.922 0.96 0.969 4.582 4.742 265.31 295.137

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.977 0.958 0.967 0.946 0.927 0.904
best 0.997 0.995 0.994 0.991 0.978 0.972
Methyl HT-SELEX, 1 experiments median 0.997 0.995 0.994 0.991 0.978 0.972
best 0.997 0.995 0.994 0.991 0.978 0.972
Non-Methyl HT-SELEX, 2 experiments median 0.757 0.746 0.741 0.731 0.715 0.706
best 0.977 0.958 0.967 0.946 0.927 0.904

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.902 0.53 0.867 0.57
batch 2 0.777 0.497 0.766 0.578
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETS-like {3.5.2.1} (TFClass)
TFClass IDTFClass: 3.5.2.1.4
HGNCHGNC:3491
MGIMGI:99253
EntrezGene (human)GeneID:2116
(SSTAR profile)
EntrezGene (mouse)GeneID:14008
(SSTAR profile)
UniProt ID (human)ETV2_HUMAN
UniProt ID (mouse)ETV2_MOUSE
UniProt AC (human)O00321
(TFClass)
UniProt AC (mouse)P41163
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
012928.51684.52944.51681.5
023468.251323.252881.251566.25
035938.0206.02815.0280.0
04132.08700.0333.074.0
058666.0571.01.01.0
060.00.09239.00.0
070.00.09239.00.0
089239.00.00.00.0
098068.047.01.01123.0
103517.045.05670.07.0
11179.01983.0302.06775.0
122828.5915.54423.51071.5
131726.752417.753471.751622.75
PFM
ACGT
010.3170.1820.3190.182
020.3750.1430.3120.17
030.6430.0220.3050.03
040.0140.9420.0360.008
050.9380.0620.00.0
060.00.01.00.0
070.00.01.00.0
081.00.00.00.0
090.8730.0050.00.122
100.3810.0050.6140.001
110.0190.2150.0330.733
120.3060.0990.4790.116
130.1870.2620.3760.176
PWM
ACGT
010.237-0.3150.243-0.317
020.406-0.5560.221-0.388
030.944-2.4070.198-2.103
04-2.8461.325-1.931-3.411
051.322-1.395-6.557-6.557
06-6.92-6.921.386-6.92
07-6.92-6.921.386-6.92
081.386-6.92-6.92-6.92
091.25-3.848-6.557-0.72
100.42-3.890.897-5.518
11-2.546-0.152-2.0281.075
120.202-0.9240.649-0.767
13-0.2910.0460.407-0.353
Standard thresholds
P-value Threshold
0.001 2.05711
0.0005 3.701085
0.0001 6.90114