ETV1.H12INVIVO.1.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV1.H12INVIVO.1.PM.A
Gene (human)	ETV1 (GeneCards)
Gene synonyms (human)	ER81
Gene (mouse)	Etv1
Gene synonyms (mouse)	Er81, Etsrp81
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	11
Consensus	vdSAGGAARYd
GC content	53.06%
Information content (bits; total / per base)	11.027 / 1.002
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (55)	0.86	0.9	0.732	0.821	0.868	0.89	2.849	3.2	165.638	255.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.979	0.961	0.957	0.938	0.819	0.833
Overall, 8 experiments	best	0.991	0.982	0.981	0.972	0.965	0.948
Methyl HT-SELEX, 3 experiments	median	0.947	0.918	0.863	0.837	0.719	0.725
Methyl HT-SELEX, 3 experiments	best	0.989	0.982	0.981	0.97	0.962	0.946
Non-Methyl HT-SELEX, 5 experiments	median	0.985	0.973	0.965	0.94	0.861	0.868
Non-Methyl HT-SELEX, 5 experiments	best	0.991	0.982	0.981	0.972	0.965	0.948

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	8.617	2.661	0.237	0.19

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.951	0.74	0.904	0.546
batch 2	0.724	0.399	0.739	0.508

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELK-like {3.5.2.2} (TFClass)
TFClass ID	TFClass: 3.5.2.2.4
HGNC	HGNC:3490
MGI	MGI:99254
EntrezGene (human)	GeneID:2115 (SSTAR profile)
EntrezGene (mouse)	GeneID:14009 (SSTAR profile)
UniProt ID (human)	ETV1_HUMAN
UniProt ID (mouse)	ETV1_MOUSE
UniProt AC (human)	P50549 (TFClass)
UniProt AC (mouse)	P41164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	ETV1.H12INVIVO.1.PM.A.pcm
PWM	ETV1.H12INVIVO.1.PM.A.pwm
PFM	ETV1.H12INVIVO.1.PM.A.pfm
Alignment	ETV1.H12INVIVO.1.PM.A.words.tsv
Threshold to P-value map	ETV1.H12INVIVO.1.PM.A.thr
Motif in other formats
JASPAR format	ETV1.H12INVIVO.1.PM.A_jaspar_format.txt
MEME format	ETV1.H12INVIVO.1.PM.A_meme_format.meme
Transfac format	ETV1.H12INVIVO.1.PM.A_transfac_format.txt
Homer format	ETV1.H12INVIVO.1.PM.A_homer_format_0.001.txt ETV1.H12INVIVO.1.PM.A_homer_format_0.0005.txt ETV1.H12INVIVO.1.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	261.0	262.0	353.0	124.0
02	452.0	93.0	311.0	144.0
03	129.0	674.0	178.0	19.0
04	773.0	202.0	19.0	6.0
05	0.0	0.0	997.0	3.0
06	3.0	0.0	997.0	0.0
07	989.0	7.0	4.0	0.0
08	733.0	7.0	12.0	248.0
09	236.0	30.0	730.0	4.0
10	68.0	155.0	84.0	693.0
11	153.0	124.0	598.0	125.0

PFM

	A	C	G	T
01	0.261	0.262	0.353	0.124
02	0.452	0.093	0.311	0.144
03	0.129	0.674	0.178	0.019
04	0.773	0.202	0.019	0.006
05	0.0	0.0	0.997	0.003
06	0.003	0.0	0.997	0.0
07	0.989	0.007	0.004	0.0
08	0.733	0.007	0.012	0.248
09	0.236	0.03	0.73	0.004
10	0.068	0.155	0.084	0.693
11	0.153	0.124	0.598	0.125

PWM

	A	C	G	T
01	0.043	0.047	0.343	-0.694
02	0.589	-0.977	0.217	-0.547
03	-0.655	0.987	-0.337	-2.497
04	1.124	-0.212	-2.497	-3.484
05	-4.982	-4.982	1.378	-3.975
06	-3.975	-4.982	1.378	-4.982
07	1.37	-3.362	-3.783	-4.982
08	1.071	-3.362	-2.909	-0.008
09	-0.057	-2.071	1.067	-3.783
10	-1.284	-0.474	-1.077	1.015
11	-0.487	-0.694	0.868	-0.686

Standard thresholds

P-value	Threshold
0.001	4.52826
0.0005	5.591025
0.0001	7.4631