ETV1.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV1.H12INVITRO.0.PSM.A
Gene (human)	ETV1 (GeneCards)
Gene synonyms (human)	ER81
Gene (mouse)	Etv1
Gene synonyms (mouse)	Er81, Etsrp81
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	nRCCGGAAGYn
GC content	57.23%
Information content (bits; total / per base)	12.497 / 1.136
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9850

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (55)	0.918	0.957	0.833	0.902	0.84	0.942	2.743	3.938	218.42	479.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.991	0.984	0.979	0.973	0.839	0.859
Overall, 8 experiments	best	0.999	0.999	0.996	0.995	0.986	0.981
Methyl HT-SELEX, 3 experiments	median	0.985	0.979	0.908	0.899	0.744	0.764
Methyl HT-SELEX, 3 experiments	best	0.99	0.982	0.985	0.975	0.973	0.959
Non-Methyl HT-SELEX, 5 experiments	median	0.997	0.996	0.988	0.98	0.881	0.894
Non-Methyl HT-SELEX, 5 experiments	best	0.999	0.999	0.996	0.995	0.986	0.981

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	17.305	3.568	0.281	0.224

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.994	0.98	0.97	0.671
batch 2	0.765	0.553	0.773	0.552

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELK-like {3.5.2.2} (TFClass)
TFClass ID	TFClass: 3.5.2.2.4
HGNC	HGNC:3490
MGI	MGI:99254
EntrezGene (human)	GeneID:2115 (SSTAR profile)
EntrezGene (mouse)	GeneID:14009 (SSTAR profile)
UniProt ID (human)	ETV1_HUMAN
UniProt ID (mouse)	ETV1_MOUSE
UniProt AC (human)	P50549 (TFClass)
UniProt AC (mouse)	P41164 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	ETV1.H12INVITRO.0.PSM.A.pcm
PWM	ETV1.H12INVITRO.0.PSM.A.pwm
PFM	ETV1.H12INVITRO.0.PSM.A.pfm
Alignment	ETV1.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	ETV1.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	ETV1.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	ETV1.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	ETV1.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	ETV1.H12INVITRO.0.PSM.A_homer_format_0.001.txt ETV1.H12INVITRO.0.PSM.A_homer_format_0.0005.txt ETV1.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2765.25	2290.25	2903.25	1891.25
02	5961.5	307.5	2360.5	1220.5
03	386.0	8923.0	509.0	32.0
04	654.0	9188.0	4.0	4.0
05	0.0	0.0	9849.0	1.0
06	0.0	0.0	9829.0	21.0
07	9848.0	1.0	0.0	1.0
08	7980.0	47.0	14.0	1809.0
09	1706.0	441.0	7635.0	68.0
10	488.25	2299.25	855.25	6207.25
11	3244.75	1816.75	2740.75	2047.75

PFM

	A	C	G	T
01	0.281	0.233	0.295	0.192
02	0.605	0.031	0.24	0.124
03	0.039	0.906	0.052	0.003
04	0.066	0.933	0.0	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.0	0.998	0.002
07	1.0	0.0	0.0	0.0
08	0.81	0.005	0.001	0.184
09	0.173	0.045	0.775	0.007
10	0.05	0.233	0.087	0.63
11	0.329	0.184	0.278	0.208

PWM

	A	C	G	T
01	0.116	-0.072	0.165	-0.264
02	0.884	-2.074	-0.042	-0.701
03	-1.848	1.287	-1.573	-4.275
04	-1.323	1.316	-5.97	-5.97
05	-6.977	-6.977	1.385	-6.616
06	-6.977	-6.977	1.383	-4.661
07	1.385	-6.616	-6.977	-6.616
08	1.175	-3.912	-5.019	-0.308
09	-0.367	-1.716	1.131	-3.557
10	-1.614	-0.069	-1.056	0.924
11	0.276	-0.304	0.107	-0.184

Standard thresholds

P-value	Threshold
0.001	3.34661
0.0005	4.832315
0.0001	7.397965