MotifETV1.H12INVITRO.0.PSM.A
Gene (human)ETV1
(GeneCards)
Gene synonyms (human)ER81
Gene (mouse)Etv1
Gene synonyms (mouse)Er81, Etsrp81
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusnRCCGGAAGYn
GC content57.23%
Information content (bits; total / per base)12.497 / 1.136
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9850

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (55) 0.918 0.957 0.833 0.902 0.84 0.942 2.743 3.938 218.42 479.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.991 0.984 0.979 0.973 0.839 0.859
best 0.999 0.999 0.996 0.995 0.986 0.981
Methyl HT-SELEX, 3 experiments median 0.985 0.979 0.908 0.899 0.744 0.764
best 0.99 0.982 0.985 0.975 0.973 0.959
Non-Methyl HT-SELEX, 5 experiments median 0.997 0.996 0.988 0.98 0.881 0.894
best 0.999 0.999 0.996 0.995 0.986 0.981

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 17.305 3.568 0.281 0.224

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.994 0.98 0.97 0.671
batch 2 0.765 0.553 0.773 0.552
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyELK-like {3.5.2.2} (TFClass)
TFClass IDTFClass: 3.5.2.2.4
HGNCHGNC:3490
MGIMGI:99254
EntrezGene (human)GeneID:2115
(SSTAR profile)
EntrezGene (mouse)GeneID:14009
(SSTAR profile)
UniProt ID (human)ETV1_HUMAN
UniProt ID (mouse)ETV1_MOUSE
UniProt AC (human)P50549
(TFClass)
UniProt AC (mouse)P41164
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
012765.252290.252903.251891.25
025961.5307.52360.51220.5
03386.08923.0509.032.0
04654.09188.04.04.0
050.00.09849.01.0
060.00.09829.021.0
079848.01.00.01.0
087980.047.014.01809.0
091706.0441.07635.068.0
10488.252299.25855.256207.25
113244.751816.752740.752047.75
PFM
ACGT
010.2810.2330.2950.192
020.6050.0310.240.124
030.0390.9060.0520.003
040.0660.9330.00.0
050.00.01.00.0
060.00.00.9980.002
071.00.00.00.0
080.810.0050.0010.184
090.1730.0450.7750.007
100.050.2330.0870.63
110.3290.1840.2780.208
PWM
ACGT
010.116-0.0720.165-0.264
020.884-2.074-0.042-0.701
03-1.8481.287-1.573-4.275
04-1.3231.316-5.97-5.97
05-6.977-6.9771.385-6.616
06-6.977-6.9771.383-4.661
071.385-6.616-6.977-6.616
081.175-3.912-5.019-0.308
09-0.367-1.7161.131-3.557
10-1.614-0.069-1.0560.924
110.276-0.3040.107-0.184
Standard thresholds
P-value Threshold
0.001 3.34661
0.0005 4.832315
0.0001 7.397965