ETS2.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETS2.H12INVIVO.1.P.B
Gene (human)	ETS2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ets2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	nvbvGGARdTSd
GC content	54.44%
Information content (bits; total / per base)	9.758 / 0.813
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.552	0.601	0.387	0.478	0.606	0.616	1.421	1.661	0	4.745
Mouse	2 (13)	0.867	0.903	0.768	0.825	0.857	0.893	3.009	3.402	133.252	165.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.902	0.857	0.838	0.794	0.725	0.709
Non-Methyl HT-SELEX, 1 experiments	best	0.902	0.857	0.838	0.794	0.725	0.709

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.666	0.22	0.524	0.311

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETS-like {3.5.2.1} (TFClass)
TFClass ID	TFClass: 3.5.2.1.2
HGNC	HGNC:3489
MGI	MGI:95456
EntrezGene (human)	GeneID:2114 (SSTAR profile)
EntrezGene (mouse)	GeneID:23872 (SSTAR profile)
UniProt ID (human)	ETS2_HUMAN
UniProt ID (mouse)	ETS2_MOUSE
UniProt AC (human)	P15036 (TFClass)
UniProt AC (mouse)	P15037 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ETS2.H12INVIVO.1.P.B.pcm
PWM	ETS2.H12INVIVO.1.P.B.pwm
PFM	ETS2.H12INVIVO.1.P.B.pfm
Alignment	ETS2.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	ETS2.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	ETS2.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	ETS2.H12INVIVO.1.P.B_meme_format.meme
Transfac format	ETS2.H12INVIVO.1.P.B_transfac_format.txt
Homer format	ETS2.H12INVIVO.1.P.B_homer_format_0.001.txt ETS2.H12INVIVO.1.P.B_homer_format_0.0005.txt ETS2.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	167.0	196.0	354.0	281.0
02	322.0	398.0	201.0	77.0
03	65.0	457.0	134.0	342.0
04	278.0	290.0	422.0	8.0
05	8.0	3.0	981.0	6.0
06	7.0	1.0	986.0	4.0
07	975.0	6.0	13.0	4.0
08	752.0	43.0	129.0	74.0
09	261.0	50.0	514.0	173.0
10	57.0	114.0	28.0	799.0
11	74.0	92.0	787.0	45.0
12	258.0	123.0	198.0	419.0

PFM

	A	C	G	T
01	0.167	0.196	0.355	0.282
02	0.323	0.399	0.201	0.077
03	0.065	0.458	0.134	0.343
04	0.279	0.291	0.423	0.008
05	0.008	0.003	0.983	0.006
06	0.007	0.001	0.988	0.004
07	0.977	0.006	0.013	0.004
08	0.754	0.043	0.129	0.074
09	0.262	0.05	0.515	0.173
10	0.057	0.114	0.028	0.801
11	0.074	0.092	0.789	0.045
12	0.259	0.123	0.198	0.42

PWM

	A	C	G	T
01	-0.398	-0.239	0.348	0.118
02	0.254	0.464	-0.214	-1.16
03	-1.326	0.602	-0.616	0.313
04	0.107	0.149	0.523	-3.252
05	-3.252	-3.973	1.364	-3.482
06	-3.36	-4.523	1.369	-3.781
07	1.358	-3.482	-2.837	-3.781
08	1.099	-1.726	-0.653	-1.199
09	0.045	-1.58	0.719	-0.363
10	-1.453	-0.775	-2.134	1.159
11	-1.199	-0.986	1.144	-1.682
12	0.033	-0.7	-0.229	0.516

Standard thresholds

P-value	Threshold
0.001	4.86362
0.0005	5.73232
0.0001	7.353595