ETS2.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETS2.H12INVITRO.1.P.B
Gene (human)	ETS2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ets2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	vvSMGGAAGYRv
GC content	57.73%
Information content (bits; total / per base)	11.246 / 0.937
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.554	0.581	0.392	0.438	0.625	0.64	1.491	1.632	0.013	4.456
Mouse	2 (13)	0.754	0.817	0.664	0.719	0.762	0.811	2.601	2.882	44.252	80.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.974	0.959	0.912	0.894	0.762	0.771
Non-Methyl HT-SELEX, 1 experiments	best	0.974	0.959	0.912	0.894	0.762	0.771

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.679	0.337	0.632	0.368

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETS-like {3.5.2.1} (TFClass)
TFClass ID	TFClass: 3.5.2.1.2
HGNC	HGNC:3489
MGI	MGI:95456
EntrezGene (human)	GeneID:2114 (SSTAR profile)
EntrezGene (mouse)	GeneID:23872 (SSTAR profile)
UniProt ID (human)	ETS2_HUMAN
UniProt ID (mouse)	ETS2_MOUSE
UniProt AC (human)	P15036 (TFClass)
UniProt AC (mouse)	P15037 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ETS2.H12INVITRO.1.P.B.pcm
PWM	ETS2.H12INVITRO.1.P.B.pwm
PFM	ETS2.H12INVITRO.1.P.B.pfm
Alignment	ETS2.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	ETS2.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	ETS2.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	ETS2.H12INVITRO.1.P.B_meme_format.meme
Transfac format	ETS2.H12INVITRO.1.P.B_transfac_format.txt
Homer format	ETS2.H12INVITRO.1.P.B_homer_format_0.001.txt ETS2.H12INVITRO.1.P.B_homer_format_0.0005.txt ETS2.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	357.0	153.0	377.0	112.0
02	450.0	111.0	370.0	68.0
03	99.0	588.0	307.0	5.0
04	422.0	520.0	47.0	10.0
05	3.0	2.0	986.0	8.0
06	5.0	2.0	991.0	1.0
07	974.0	9.0	15.0	1.0
08	973.0	3.0	12.0	11.0
09	172.0	36.0	775.0	16.0
10	113.0	226.0	73.0	587.0
11	166.0	121.0	607.0	105.0
12	298.0	229.0	361.0	111.0

PFM

	A	C	G	T
01	0.357	0.153	0.377	0.112
02	0.45	0.111	0.37	0.068
03	0.099	0.589	0.307	0.005
04	0.422	0.521	0.047	0.01
05	0.003	0.002	0.987	0.008
06	0.005	0.002	0.992	0.001
07	0.975	0.009	0.015	0.001
08	0.974	0.003	0.012	0.011
09	0.172	0.036	0.776	0.016
10	0.113	0.226	0.073	0.588
11	0.166	0.121	0.608	0.105
12	0.298	0.229	0.361	0.111

PWM

	A	C	G	T
01	0.355	-0.486	0.409	-0.794
02	0.586	-0.802	0.391	-1.283
03	-0.915	0.852	0.205	-3.621
04	0.522	0.73	-1.641	-3.065
05	-3.974	-4.212	1.368	-3.252
06	-3.621	-4.212	1.373	-4.524
07	1.356	-3.155	-2.71	-4.524
08	1.355	-3.974	-2.908	-2.984
09	-0.37	-1.897	1.128	-2.652
10	-0.785	-0.099	-1.214	0.851
11	-0.405	-0.717	0.884	-0.857
12	0.176	-0.086	0.366	-0.802

Standard thresholds

P-value	Threshold
0.001	4.307775
0.0005	5.395415
0.0001	7.498