ETS2.H12INVITRO.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETS2.H12INVITRO.0.S.C
Gene (human)	ETS2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ets2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	19
Consensus	ndCCGGAARYvbddvbbnn
GC content	57.32%
Information content (bits; total / per base)	13.528 / 0.712
Data sources	HT-SELEX
Aligned words	9942

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.568	0.584	0.413	0.443	0.537	0.572	1.175	1.378	0	3.745
Mouse	2 (13)	0.775	0.827	0.68	0.721	0.737	0.776	2.414	2.549	54.921	86.367

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.952	0.949	0.771	0.799
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.952	0.949	0.771	0.799

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.741	0.377	0.602	0.299

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETS-like {3.5.2.1} (TFClass)
TFClass ID	TFClass: 3.5.2.1.2
HGNC	HGNC:3489
MGI	MGI:95456
EntrezGene (human)	GeneID:2114 (SSTAR profile)
EntrezGene (mouse)	GeneID:23872 (SSTAR profile)
UniProt ID (human)	ETS2_HUMAN
UniProt ID (mouse)	ETS2_MOUSE
UniProt AC (human)	P15036 (TFClass)
UniProt AC (mouse)	P15037 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ETS2.H12INVITRO.0.S.C.pcm
PWM	ETS2.H12INVITRO.0.S.C.pwm
PFM	ETS2.H12INVITRO.0.S.C.pfm
Alignment	ETS2.H12INVITRO.0.S.C.words.tsv
Threshold to P-value map	ETS2.H12INVITRO.0.S.C.thr
Motif in other formats
JASPAR format	ETS2.H12INVITRO.0.S.C_jaspar_format.txt
MEME format	ETS2.H12INVITRO.0.S.C_meme_format.meme
Transfac format	ETS2.H12INVITRO.0.S.C_transfac_format.txt
Homer format	ETS2.H12INVITRO.0.S.C_homer_format_0.001.txt ETS2.H12INVITRO.0.S.C_homer_format_0.0005.txt ETS2.H12INVITRO.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2477.75	2521.75	2703.75	2238.75
02	5568.0	672.0	2178.0	1524.0
03	420.0	8257.0	1209.0	56.0
04	653.0	9200.0	70.0	19.0
05	1.0	1.0	9931.0	9.0
06	4.0	0.0	9934.0	4.0
07	9860.0	18.0	5.0	59.0
08	7674.0	65.0	19.0	2184.0
09	2736.0	139.0	6999.0	68.0
10	252.0	3117.0	503.0	6070.0
11	3145.0	1459.0	4335.0	1003.0
12	1293.0	4706.0	2177.0	1766.0
13	3140.0	1283.0	2098.0	3421.0
14	1607.0	1324.0	1602.0	5409.0
15	1459.0	5501.0	1606.0	1376.0
16	1311.0	5660.0	1454.0	1517.0
17	1413.0	1598.0	4647.0	2284.0
18	1778.75	2494.75	3806.75	1861.75
19	2270.5	2555.5	2422.5	2693.5

PFM

	A	C	G	T
01	0.249	0.254	0.272	0.225
02	0.56	0.068	0.219	0.153
03	0.042	0.831	0.122	0.006
04	0.066	0.925	0.007	0.002
05	0.0	0.0	0.999	0.001
06	0.0	0.0	0.999	0.0
07	0.992	0.002	0.001	0.006
08	0.772	0.007	0.002	0.22
09	0.275	0.014	0.704	0.007
10	0.025	0.314	0.051	0.611
11	0.316	0.147	0.436	0.101
12	0.13	0.473	0.219	0.178
13	0.316	0.129	0.211	0.344
14	0.162	0.133	0.161	0.544
15	0.147	0.553	0.162	0.138
16	0.132	0.569	0.146	0.153
17	0.142	0.161	0.467	0.23
18	0.179	0.251	0.383	0.187
19	0.228	0.257	0.244	0.271

PWM

	A	C	G	T
01	-0.003	0.014	0.084	-0.104
02	0.806	-1.305	-0.132	-0.489
03	-1.773	1.2	-0.72	-3.754
04	-1.334	1.308	-3.538	-4.76
05	-6.625	-6.625	1.384	-5.394
06	-5.978	-6.986	1.385	-5.978
07	1.377	-4.808	-5.831	-3.703
08	1.127	-3.61	-4.76	-0.129
09	0.096	-2.868	1.035	-3.566
10	-2.281	0.226	-1.594	0.892
11	0.235	-0.532	0.556	-0.906
12	-0.653	0.638	-0.132	-0.341
13	0.234	-0.66	-0.169	0.319
14	-0.436	-0.629	-0.439	0.777
15	-0.532	0.794	-0.436	-0.591
16	-0.639	0.822	-0.535	-0.493
17	-0.564	-0.441	0.625	-0.084
18	-0.334	0.004	0.426	-0.289
19	-0.09	0.028	-0.026	0.08

Standard thresholds

P-value	Threshold
0.001	3.09356
0.0005	4.45236
0.0001	7.07066