| Motif | ETS1.H12INVITRO.0.S.B |
| Gene (human) | ETS1 (GeneCards) |
| Gene synonyms (human) | EWSR2 |
| Gene (mouse) | Ets1 |
| Gene synonyms (mouse) | Ets-1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | ETS1.H12INVITRO.0.S.B |
| Gene (human) | ETS1 (GeneCards) |
| Gene synonyms (human) | EWSR2 |
| Gene (mouse) | Ets1 |
| Gene synonyms (mouse) | Ets-1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | dSMGGAARYd |
| GC content | 54.36% |
| Information content (bits; total / per base) | 10.573 / 1.057 |
| Data sources | HT-SELEX |
| Aligned words | 6094 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 19 (119) | 0.843 | 0.941 | 0.765 | 0.891 | 0.805 | 0.903 | 2.473 | 3.316 | 82.745 | 232.678 |
| Mouse | 13 (75) | 0.857 | 0.946 | 0.776 | 0.902 | 0.833 | 0.913 | 2.737 | 3.55 | 96.553 | 289.469 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 4 experiments | median | 0.814 | 0.805 | 0.648 | 0.666 | 0.561 | 0.592 |
| best | 0.988 | 0.984 | 0.843 | 0.853 | 0.675 | 0.713 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 7.309 | 21.234 | 0.356 | 0.255 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Tryptophan cluster factors {3.5} (TFClass) |
| TF family | Ets-related {3.5.2} (TFClass) |
| TF subfamily | ETS-like {3.5.2.1} (TFClass) |
| TFClass ID | TFClass: 3.5.2.1.1 |
| HGNC | HGNC:3488 |
| MGI | MGI:95455 |
| EntrezGene (human) | GeneID:2113 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:23871 (SSTAR profile) |
| UniProt ID (human) | ETS1_HUMAN |
| UniProt ID (mouse) | ETS1_MOUSE |
| UniProt AC (human) | P14921 (TFClass) |
| UniProt AC (mouse) | P27577 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 19 human, 13 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 0 |
| PCM | ETS1.H12INVITRO.0.S.B.pcm |
| PWM | ETS1.H12INVITRO.0.S.B.pwm |
| PFM | ETS1.H12INVITRO.0.S.B.pfm |
| Alignment | ETS1.H12INVITRO.0.S.B.words.tsv |
| Threshold to P-value map | ETS1.H12INVITRO.0.S.B.thr |
| Motif in other formats | |
| JASPAR format | ETS1.H12INVITRO.0.S.B_jaspar_format.txt |
| MEME format | ETS1.H12INVITRO.0.S.B_meme_format.meme |
| Transfac format | ETS1.H12INVITRO.0.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 3076.5 | 828.5 | 1275.5 | 913.5 |
| 02 | 1037.5 | 3635.5 | 1054.5 | 366.5 |
| 03 | 943.0 | 4700.0 | 382.0 | 69.0 |
| 04 | 0.0 | 0.0 | 6091.0 | 3.0 |
| 05 | 0.0 | 0.0 | 6094.0 | 0.0 |
| 06 | 6094.0 | 0.0 | 0.0 | 0.0 |
| 07 | 5258.0 | 7.0 | 3.0 | 826.0 |
| 08 | 1961.0 | 75.0 | 3982.0 | 76.0 |
| 09 | 365.0 | 1409.0 | 550.0 | 3770.0 |
| 10 | 1942.75 | 890.75 | 2146.75 | 1113.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.505 | 0.136 | 0.209 | 0.15 |
| 02 | 0.17 | 0.597 | 0.173 | 0.06 |
| 03 | 0.155 | 0.771 | 0.063 | 0.011 |
| 04 | 0.0 | 0.0 | 1.0 | 0.0 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.863 | 0.001 | 0.0 | 0.136 |
| 08 | 0.322 | 0.012 | 0.653 | 0.012 |
| 09 | 0.06 | 0.231 | 0.09 | 0.619 |
| 10 | 0.319 | 0.146 | 0.352 | 0.183 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.702 | -0.608 | -0.177 | -0.511 |
| 02 | -0.384 | 0.869 | -0.367 | -1.42 |
| 03 | -0.479 | 1.126 | -1.379 | -3.065 |
| 04 | -6.551 | -6.551 | 1.385 | -5.686 |
| 05 | -6.551 | -6.551 | 1.385 | -6.551 |
| 06 | 1.385 | -6.551 | -6.551 | -6.551 |
| 07 | 1.238 | -5.113 | -5.686 | -0.611 |
| 08 | 0.252 | -2.984 | 0.96 | -2.971 |
| 09 | -1.424 | -0.078 | -1.016 | 0.905 |
| 10 | 0.243 | -0.536 | 0.343 | -0.313 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.790685 |
| 0.0005 | 5.842455 |
| 0.0001 | 7.56334 |