MotifESX1.H12INVIVO.1.S.D
Gene (human)ESX1
(GeneCards)
Gene synonyms (human)ESX1L, ESX1R
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length17
ConsensushWWhhnRYTAATTASbn
GC content28.21%
Information content (bits; total / per base)15.186 / 0.893
Data sourcesHT-SELEX
Aligned words692

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.967 0.943 0.951 0.922 0.929 0.893
best 0.993 0.987 0.988 0.981 0.977 0.966
Methyl HT-SELEX, 3 experiments median 0.962 0.932 0.952 0.92 0.93 0.895
best 0.978 0.96 0.973 0.952 0.961 0.938
Non-Methyl HT-SELEX, 7 experiments median 0.972 0.954 0.951 0.923 0.927 0.89
best 0.993 0.987 0.988 0.981 0.977 0.966

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.973 0.481 0.947 0.56
batch 2 0.675 0.471 0.726 0.531
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyESX {3.1.3.8} (TFClass)
TFClass IDTFClass: 3.1.3.8.1
HGNCHGNC:14865
MGI
EntrezGene (human)GeneID:80712
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)ESX1_HUMAN
UniProt ID (mouse)
UniProt AC (human)Q8N693
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
01240.25124.2571.25256.25
02299.546.521.5324.5
03392.036.057.0207.0
04285.067.041.0299.0
05119.091.075.0407.0
06209.0152.0157.0174.0
07360.053.0266.013.0
082.0395.068.0227.0
090.0117.00.0575.0
10691.00.01.00.0
11692.00.00.00.0
120.00.00.0692.0
130.02.00.0690.0
14659.00.033.00.0
1588.0108.0484.012.0
1687.75289.75174.75139.75
17190.0132.0256.0114.0
PFM
ACGT
010.3470.180.1030.37
020.4330.0670.0310.469
030.5660.0520.0820.299
040.4120.0970.0590.432
050.1720.1320.1080.588
060.3020.220.2270.251
070.520.0770.3840.019
080.0030.5710.0980.328
090.00.1690.00.831
100.9990.00.0010.0
111.00.00.00.0
120.00.00.01.0
130.00.0030.00.997
140.9520.00.0480.0
150.1270.1560.6990.017
160.1270.4190.2530.202
170.2750.1910.370.165
PWM
ACGT
010.326-0.327-0.8740.39
020.545-1.289-2.0210.625
030.813-1.535-1.0910.178
040.496-0.934-1.410.543
05-0.37-0.634-0.8240.85
060.187-0.128-0.0960.006
070.728-1.1620.427-2.479
08-3.8720.82-0.9190.269
09-4.671-0.387-4.6711.195
101.378-4.671-4.194-4.671
111.379-4.671-4.671-4.671
12-4.671-4.671-4.6711.379
13-4.671-3.872-4.6711.376
141.331-4.671-1.618-4.671
15-0.667-0.4661.023-2.55
16-0.670.5120.01-0.211
170.093-0.2680.389-0.412
Standard thresholds
P-value Threshold
0.001 2.21006
0.0005 3.58016
0.0001 6.51796