MotifESX1.H12INVIVO.0.SM.D
Gene (human)ESX1
(GeneCards)
Gene synonyms (human)ESX1L, ESX1R
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length11
ConsensusnnYRATTAvbn
GC content36.35%
Information content (bits; total / per base)9.768 / 0.888
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9416

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.975 0.958 0.965 0.943 0.939 0.916
best 0.993 0.988 0.988 0.981 0.976 0.965
Methyl HT-SELEX, 3 experiments median 0.977 0.961 0.965 0.944 0.943 0.917
best 0.988 0.979 0.983 0.971 0.972 0.957
Non-Methyl HT-SELEX, 7 experiments median 0.974 0.956 0.964 0.942 0.937 0.914
best 0.993 0.988 0.988 0.981 0.976 0.965

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.994 0.772 0.965 0.598
batch 2 0.714 0.484 0.757 0.545
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyESX {3.1.3.8} (TFClass)
TFClass IDTFClass: 3.1.3.8.1
HGNCHGNC:14865
MGI
EntrezGene (human)GeneID:80712
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)ESX1_HUMAN
UniProt ID (mouse)
UniProt AC (human)Q8N693
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
012579.52688.52437.51710.5
021661.02624.03251.01880.0
03287.03540.0286.05303.0
045650.01203.02462.0101.0
059283.0102.030.01.0
060.00.00.09416.0
070.022.00.09394.0
089395.00.021.00.0
092181.02254.04434.0547.0
10465.254242.252719.251989.25
111890.752345.752990.752188.75
PFM
ACGT
010.2740.2860.2590.182
020.1760.2790.3450.2
030.030.3760.030.563
040.60.1280.2610.011
050.9860.0110.0030.0
060.00.00.01.0
070.00.0020.00.998
080.9980.00.0020.0
090.2320.2390.4710.058
100.0490.4510.2890.211
110.2010.2490.3180.232
PWM
ACGT
010.0910.1330.035-0.319
02-0.3480.1080.323-0.225
03-2.0970.408-2.1010.812
040.875-0.670.045-3.127
051.371-3.118-4.29-6.575
06-6.937-6.937-6.9371.386
07-6.937-4.575-6.9371.383
081.383-6.937-4.617-6.937
09-0.076-0.0430.633-1.456
10-1.6170.5890.144-0.168
11-0.219-0.0040.239-0.073
Standard thresholds
P-value Threshold
0.001 5.19324
0.0005 6.279515
0.0001 7.58244