| Motif | ESX1.H12CORE.0.SM.B |
| Gene (human) | ESX1 (GeneCards) |
| Gene synonyms (human) | ESX1L, ESX1R |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | ESX1.H12CORE.0.SM.B |
| Gene (human) | ESX1 (GeneCards) |
| Gene synonyms (human) | ESX1L, ESX1R |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 11 |
| Consensus | nnYRATTAvbn |
| GC content | 36.35% |
| Information content (bits; total / per base) | 9.768 / 0.888 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9416 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 10 experiments | median | 0.975 | 0.958 | 0.965 | 0.943 | 0.939 | 0.916 |
| best | 0.993 | 0.988 | 0.988 | 0.981 | 0.976 | 0.965 | |
| Methyl HT-SELEX, 3 experiments | median | 0.977 | 0.961 | 0.965 | 0.944 | 0.943 | 0.917 |
| best | 0.988 | 0.979 | 0.983 | 0.971 | 0.972 | 0.957 | |
| Non-Methyl HT-SELEX, 7 experiments | median | 0.974 | 0.956 | 0.964 | 0.942 | 0.937 | 0.914 |
| best | 0.993 | 0.988 | 0.988 | 0.981 | 0.976 | 0.965 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.994 | 0.772 | 0.965 | 0.598 |
| batch 2 | 0.714 | 0.484 | 0.757 | 0.545 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | ESX {3.1.3.8} (TFClass) |
| TFClass ID | TFClass: 3.1.3.8.1 |
| HGNC | HGNC:14865 |
| MGI | |
| EntrezGene (human) | GeneID:80712 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | ESX1_HUMAN |
| UniProt ID (mouse) | |
| UniProt AC (human) | Q8N693 (TFClass) |
| UniProt AC (mouse) | |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 7 |
| Methyl-HT-SELEX | 3 |
| PCM | ESX1.H12CORE.0.SM.B.pcm |
| PWM | ESX1.H12CORE.0.SM.B.pwm |
| PFM | ESX1.H12CORE.0.SM.B.pfm |
| Alignment | ESX1.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | ESX1.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | ESX1.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | ESX1.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | ESX1.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2579.5 | 2688.5 | 2437.5 | 1710.5 |
| 02 | 1661.0 | 2624.0 | 3251.0 | 1880.0 |
| 03 | 287.0 | 3540.0 | 286.0 | 5303.0 |
| 04 | 5650.0 | 1203.0 | 2462.0 | 101.0 |
| 05 | 9283.0 | 102.0 | 30.0 | 1.0 |
| 06 | 0.0 | 0.0 | 0.0 | 9416.0 |
| 07 | 0.0 | 22.0 | 0.0 | 9394.0 |
| 08 | 9395.0 | 0.0 | 21.0 | 0.0 |
| 09 | 2181.0 | 2254.0 | 4434.0 | 547.0 |
| 10 | 465.25 | 4242.25 | 2719.25 | 1989.25 |
| 11 | 1890.75 | 2345.75 | 2990.75 | 2188.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.274 | 0.286 | 0.259 | 0.182 |
| 02 | 0.176 | 0.279 | 0.345 | 0.2 |
| 03 | 0.03 | 0.376 | 0.03 | 0.563 |
| 04 | 0.6 | 0.128 | 0.261 | 0.011 |
| 05 | 0.986 | 0.011 | 0.003 | 0.0 |
| 06 | 0.0 | 0.0 | 0.0 | 1.0 |
| 07 | 0.0 | 0.002 | 0.0 | 0.998 |
| 08 | 0.998 | 0.0 | 0.002 | 0.0 |
| 09 | 0.232 | 0.239 | 0.471 | 0.058 |
| 10 | 0.049 | 0.451 | 0.289 | 0.211 |
| 11 | 0.201 | 0.249 | 0.318 | 0.232 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.091 | 0.133 | 0.035 | -0.319 |
| 02 | -0.348 | 0.108 | 0.323 | -0.225 |
| 03 | -2.097 | 0.408 | -2.101 | 0.812 |
| 04 | 0.875 | -0.67 | 0.045 | -3.127 |
| 05 | 1.371 | -3.118 | -4.29 | -6.575 |
| 06 | -6.937 | -6.937 | -6.937 | 1.386 |
| 07 | -6.937 | -4.575 | -6.937 | 1.383 |
| 08 | 1.383 | -6.937 | -4.617 | -6.937 |
| 09 | -0.076 | -0.043 | 0.633 | -1.456 |
| 10 | -1.617 | 0.589 | 0.144 | -0.168 |
| 11 | -0.219 | -0.004 | 0.239 | -0.073 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.19324 |
| 0.0005 | 6.279515 |
| 0.0001 | 7.58244 |