MotifESR2.H12INVIVO.1.P.B
Gene (human)ESR2
(GeneCards)
Gene synonyms (human)ESTRB, NR3A2
Gene (mouse)Esr2
Gene synonyms (mouse)Estrb, Nr3a2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length7
ConsensusRGGTCAb
GC content59.11%
Information content (bits; total / per base)9.419 / 1.346
Data sourcesChIP-Seq
Aligned words1009

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (42) 0.834 0.877 0.698 0.767 0.785 0.826 1.965 2.14 164.821 239.201
Mouse 3 (19) 0.642 0.867 0.507 0.738 0.576 0.817 1.239 2.093 27.398 91.886

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.317 2.252 0.172 0.12
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyER-like (NR3A) {2.1.1.2} (TFClass)
TFClass IDTFClass: 2.1.1.2.2
HGNCHGNC:3468
MGIMGI:109392
EntrezGene (human)GeneID:2100
(SSTAR profile)
EntrezGene (mouse)GeneID:13983
(SSTAR profile)
UniProt ID (human)ESR2_HUMAN
UniProt ID (mouse)ESR2_MOUSE
UniProt AC (human)Q92731
(TFClass)
UniProt AC (mouse)O08537
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 3 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01679.039.0276.015.0
0220.01.0935.053.0
037.015.0978.09.0
0416.06.065.0922.0
056.0990.04.09.0
06951.02.054.02.0
0784.0457.0353.0115.0
PFM
ACGT
010.6730.0390.2740.015
020.020.0010.9270.053
030.0070.0150.9690.009
040.0160.0060.0640.914
050.0060.9810.0040.009
060.9430.0020.0540.002
070.0830.4530.350.114
PWM
ACGT
010.986-1.830.089-2.72
02-2.459-4.5331.305-1.535
03-3.371-2.721.35-3.164
04-2.662-3.492-1.3371.291
05-3.4921.362-3.792-3.164
061.322-4.221-1.517-4.221
07-1.0860.5910.334-0.777
Standard thresholds
P-value Threshold
0.001 4.623345
0.0005 5.49817
0.0001 7.67608