MotifESR2.H12INVITRO.1.P.D
Gene (human)ESR2
(GeneCards)
Gene synonyms (human)ESTRB, NR3A2
Gene (mouse)Esr2
Gene synonyms (mouse)Estrb, Nr3a2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length7
ConsensusRGGTCAb
GC content60.05%
Information content (bits; total / per base)9.645 / 1.378
Data sourcesChIP-Seq
Aligned words1021

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (42) 0.834 0.876 0.697 0.765 0.779 0.824 1.963 2.136 162.677 236.523
Mouse 3 (19) 0.65 0.866 0.505 0.737 0.579 0.817 1.243 2.092 30.959 91.469

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.722 3.041 0.176 0.125
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyER-like (NR3A) {2.1.1.2} (TFClass)
TFClass IDTFClass: 2.1.1.2.2
HGNCHGNC:3468
MGIMGI:109392
EntrezGene (human)GeneID:2100
(SSTAR profile)
EntrezGene (mouse)GeneID:13983
(SSTAR profile)
UniProt ID (human)ESR2_HUMAN
UniProt ID (mouse)ESR2_MOUSE
UniProt AC (human)Q92731
(TFClass)
UniProt AC (mouse)O08537
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 3 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01676.053.0288.04.0
0225.01.0972.023.0
037.010.01002.02.0
0417.08.073.0923.0
053.01005.02.011.0
06967.01.051.02.0
0789.0465.0361.0106.0
PFM
ACGT
010.6620.0520.2820.004
020.0240.0010.9520.023
030.0070.010.9810.002
040.0170.0080.0710.904
050.0030.9840.0020.011
060.9470.0010.050.002
070.0870.4550.3540.104
PWM
ACGT
010.97-1.5470.12-3.803
02-2.263-4.5441.332-2.341
03-3.382-3.0871.362-4.232
04-2.619-3.274-1.2351.28
05-3.9951.365-4.232-3.005
061.327-4.544-1.584-4.232
07-1.0410.5970.345-0.869
Standard thresholds
P-value Threshold
0.001 4.59294
0.0005 5.719835
0.0001 7.72584