ESR2.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ESR2.H12INVITRO.0.P.D
Gene (human)	ESR2 (GeneCards)
Gene synonyms (human)	ESTRB, NR3A2
Gene (mouse)	Esr2
Gene synonyms (mouse)	Estrb, Nr3a2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	15
Consensus	RGGKCRvCbYGhCCY
GC content	63.25%
Information content (bits; total / per base)	11.965 / 0.798
Data sources	ChIP-Seq
Aligned words	1004

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (42)	0.907	0.935	0.833	0.877	0.892	0.915	3.611	3.777	339.664	430.854
Mouse	3 (19)	0.755	0.924	0.684	0.865	0.749	0.917	2.846	4.629	114.658	164.284

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.7	11.184	0.252	0.211

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	ER-like (NR3A) {2.1.1.2} (TFClass)
TFClass ID	TFClass: 2.1.1.2.2
HGNC	HGNC:3468
MGI	MGI:109392
EntrezGene (human)	GeneID:2100 (SSTAR profile)
EntrezGene (mouse)	GeneID:13983 (SSTAR profile)
UniProt ID (human)	ESR2_HUMAN
UniProt ID (mouse)	ESR2_MOUSE
UniProt AC (human)	Q92731 (TFClass)
UniProt AC (mouse)	O08537 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 3 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	ESR2.H12INVITRO.0.P.D.pcm
PWM	ESR2.H12INVITRO.0.P.D.pwm
PFM	ESR2.H12INVITRO.0.P.D.pfm
Alignment	ESR2.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	ESR2.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	ESR2.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	ESR2.H12INVITRO.0.P.D_meme_format.meme
Transfac format	ESR2.H12INVITRO.0.P.D_transfac_format.txt
Homer format	ESR2.H12INVITRO.0.P.D_homer_format_0.001.txt ESR2.H12INVITRO.0.P.D_homer_format_0.0005.txt ESR2.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	520.0	85.0	364.0	35.0
02	101.0	5.0	823.0	75.0
03	65.0	32.0	868.0	39.0
04	83.0	105.0	228.0	588.0
05	7.0	823.0	66.0	108.0
06	720.0	22.0	208.0	54.0
07	109.0	522.0	287.0	86.0
08	319.0	685.0	0.0	0.0
09	149.0	384.0	307.0	164.0
10	94.0	198.0	47.0	665.0
11	82.0	40.0	880.0	2.0
12	527.0	266.0	97.0	114.0
13	26.0	874.0	29.0	75.0
14	70.0	844.0	7.0	83.0
15	54.0	360.0	69.0	521.0

PFM

	A	C	G	T
01	0.518	0.085	0.363	0.035
02	0.101	0.005	0.82	0.075
03	0.065	0.032	0.865	0.039
04	0.083	0.105	0.227	0.586
05	0.007	0.82	0.066	0.108
06	0.717	0.022	0.207	0.054
07	0.109	0.52	0.286	0.086
08	0.318	0.682	0.0	0.0
09	0.148	0.382	0.306	0.163
10	0.094	0.197	0.047	0.662
11	0.082	0.04	0.876	0.002
12	0.525	0.265	0.097	0.114
13	0.026	0.871	0.029	0.075
14	0.07	0.841	0.007	0.083
15	0.054	0.359	0.069	0.519

PWM

	A	C	G	T
01	0.725	-1.07	0.37	-1.929
02	-0.9	-3.626	1.183	-1.192
03	-1.332	-2.014	1.236	-1.825
04	-1.093	-0.862	-0.095	0.847
05	-3.366	1.183	-1.317	-0.834
06	1.049	-2.366	-0.187	-1.512
07	-0.825	0.729	0.133	-1.058
08	0.238	1.0	-4.985	-4.985
09	-0.517	0.423	0.2	-0.422
10	-0.971	-0.235	-1.646	0.97
11	-1.105	-1.801	1.25	-4.216
12	0.738	0.058	-0.94	-0.781
13	-2.21	1.243	-2.107	-1.192
14	-1.259	1.208	-3.366	-1.093
15	-1.512	0.359	-1.273	0.727

Standard thresholds

P-value	Threshold
0.001	4.26471
0.0005	5.18246
0.0001	7.09171