| Motif | ESR1.H12INVIVO.1.P.B |
| Gene (human) | ESR1 (GeneCards) |
| Gene synonyms (human) | ESR, NR3A1 |
| Gene (mouse) | Esr1 |
| Gene synonyms (mouse) | Esr, Estr, Estra, Nr3a1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | ESR1.H12INVIVO.1.P.B |
| Gene (human) | ESR1 (GeneCards) |
| Gene synonyms (human) | ESR, NR3A1 |
| Gene (mouse) | Esr1 |
| Gene synonyms (mouse) | Esr, Estr, Estra, Nr3a1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 9 |
| Consensus | vTGACCYdv |
| GC content | 56.96% |
| Information content (bits; total / per base) | 9.603 / 1.067 |
| Data sources | ChIP-Seq |
| Aligned words | 428 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 269 (425) | 0.837 | 0.912 | 0.725 | 0.858 | 0.798 | 0.878 | 2.329 | 2.749 | 163.959 | 424.208 |
| Mouse | 22 (29) | 0.869 | 0.896 | 0.746 | 0.818 | 0.831 | 0.868 | 2.428 | 2.737 | 216.481 | 403.921 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.734 | 0.672 | 0.655 | 0.621 | 0.59 | 0.58 |
| best | 0.734 | 0.672 | 0.655 | 0.621 | 0.59 | 0.58 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 1.825 | 9.804 | 0.082 | 0.092 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Steroid hormone receptors {2.1.1} (TFClass) |
| TF subfamily | ER-like (NR3A) {2.1.1.2} (TFClass) |
| TFClass ID | TFClass: 2.1.1.2.1 |
| HGNC | HGNC:3467 |
| MGI | MGI:1352467 |
| EntrezGene (human) | GeneID:2099 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13982 (SSTAR profile) |
| UniProt ID (human) | ESR1_HUMAN |
| UniProt ID (mouse) | ESR1_MOUSE |
| UniProt AC (human) | P03372 (TFClass) |
| UniProt AC (mouse) | P19785 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 269 human, 22 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| PCM | ESR1.H12INVIVO.1.P.B.pcm |
| PWM | ESR1.H12INVIVO.1.P.B.pwm |
| PFM | ESR1.H12INVIVO.1.P.B.pfm |
| Alignment | ESR1.H12INVIVO.1.P.B.words.tsv |
| Threshold to P-value map | ESR1.H12INVIVO.1.P.B.thr |
| Motif in other formats | |
| JASPAR format | ESR1.H12INVIVO.1.P.B_jaspar_format.txt |
| MEME format | ESR1.H12INVIVO.1.P.B_meme_format.meme |
| Transfac format | ESR1.H12INVIVO.1.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 85.0 | 126.0 | 186.0 | 31.0 |
| 02 | 7.0 | 4.0 | 3.0 | 414.0 |
| 03 | 3.0 | 3.0 | 416.0 | 6.0 |
| 04 | 380.0 | 35.0 | 7.0 | 6.0 |
| 05 | 1.0 | 420.0 | 2.0 | 5.0 |
| 06 | 51.0 | 372.0 | 0.0 | 5.0 |
| 07 | 7.0 | 120.0 | 3.0 | 298.0 |
| 08 | 125.0 | 46.0 | 179.0 | 78.0 |
| 09 | 93.0 | 83.0 | 189.0 | 63.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.199 | 0.294 | 0.435 | 0.072 |
| 02 | 0.016 | 0.009 | 0.007 | 0.967 |
| 03 | 0.007 | 0.007 | 0.972 | 0.014 |
| 04 | 0.888 | 0.082 | 0.016 | 0.014 |
| 05 | 0.002 | 0.981 | 0.005 | 0.012 |
| 06 | 0.119 | 0.869 | 0.0 | 0.012 |
| 07 | 0.016 | 0.28 | 0.007 | 0.696 |
| 08 | 0.292 | 0.107 | 0.418 | 0.182 |
| 09 | 0.217 | 0.194 | 0.442 | 0.147 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.227 | 0.161 | 0.547 | -1.205 |
| 02 | -2.545 | -2.979 | -3.18 | 1.343 |
| 03 | -3.18 | -3.18 | 1.347 | -2.67 |
| 04 | 1.257 | -1.089 | -2.545 | -2.67 |
| 05 | -3.765 | 1.357 | -3.43 | -2.813 |
| 06 | -0.726 | 1.236 | -4.272 | -2.813 |
| 07 | -2.545 | 0.113 | -3.18 | 1.015 |
| 08 | 0.153 | -0.826 | 0.509 | -0.311 |
| 09 | -0.138 | -0.25 | 0.563 | -0.52 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.75146 |
| 0.0005 | 5.82232 |
| 0.0001 | 7.57739 |