ERR3.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ERR3.H12INVIVO.0.PSM.A
Gene (human)	ESRRG (GeneCards)
Gene synonyms (human)	ERR3, ERRG2, KIAA0832, NR3B3
Gene (mouse)	Esrrg
Gene synonyms (mouse)	Err3, Kiaa0832, Nr3b3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	bYSAAGGTCAh
GC content	53.34%
Information content (bits; total / per base)	12.964 / 1.179
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	1007

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (19)	0.896	0.934	0.804	0.866	0.909	0.935	3.949	4.381	155.553	316.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.992	0.987	0.981	0.973	0.929	0.918
Overall, 6 experiments	best	0.997	0.994	0.994	0.99	0.983	0.976
Methyl HT-SELEX, 2 experiments	median	0.995	0.991	0.988	0.983	0.959	0.95
Methyl HT-SELEX, 2 experiments	best	0.996	0.993	0.993	0.989	0.983	0.976
Non-Methyl HT-SELEX, 4 experiments	median	0.865	0.864	0.794	0.798	0.738	0.742
Non-Methyl HT-SELEX, 4 experiments	best	0.997	0.994	0.994	0.99	0.982	0.976

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	ER-like (NR3A) {2.1.1.2} (TFClass)
TFClass ID	TFClass: 2.1.1.2.5
HGNC	HGNC:3474
MGI	MGI:1347056
EntrezGene (human)	GeneID:2104 (SSTAR profile)
EntrezGene (mouse)	GeneID:26381 (SSTAR profile)
UniProt ID (human)	ERR3_HUMAN
UniProt ID (mouse)	ERR3_MOUSE
UniProt AC (human)	P62508 (TFClass)
UniProt AC (mouse)	P62509 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	ERR3.H12INVIVO.0.PSM.A.pcm
PWM	ERR3.H12INVIVO.0.PSM.A.pwm
PFM	ERR3.H12INVIVO.0.PSM.A.pfm
Alignment	ERR3.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	ERR3.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	ERR3.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	ERR3.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	ERR3.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	ERR3.H12INVIVO.0.PSM.A_homer_format_0.001.txt ERR3.H12INVIVO.0.PSM.A_homer_format_0.0005.txt ERR3.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	80.0	343.0	273.0	311.0
02	36.0	390.0	82.0	499.0
03	59.0	753.0	192.0	3.0
04	922.0	11.0	72.0	2.0
05	982.0	4.0	18.0	3.0
06	9.0	2.0	981.0	15.0
07	2.0	2.0	1002.0	1.0
08	64.0	7.0	100.0	836.0
09	2.0	912.0	68.0	25.0
10	933.0	11.0	60.0	3.0
11	192.0	442.0	183.0	190.0

PFM

	A	C	G	T
01	0.079	0.341	0.271	0.309
02	0.036	0.387	0.081	0.496
03	0.059	0.748	0.191	0.003
04	0.916	0.011	0.071	0.002
05	0.975	0.004	0.018	0.003
06	0.009	0.002	0.974	0.015
07	0.002	0.002	0.995	0.001
08	0.064	0.007	0.099	0.83
09	0.002	0.906	0.068	0.025
10	0.927	0.011	0.06	0.003
11	0.191	0.439	0.182	0.189

PWM

	A	C	G	T
01	-1.132	0.307	0.081	0.21
02	-1.905	0.435	-1.108	0.681
03	-1.429	1.091	-0.269	-3.982
04	1.293	-2.991	-1.235	-4.219
05	1.356	-3.79	-2.553	-3.982
06	-3.162	-4.219	1.355	-2.718
07	-4.219	-4.219	1.376	-4.531
08	-1.35	-3.369	-0.913	1.195
09	-4.219	1.282	-1.291	-2.25
10	1.305	-2.991	-1.413	-3.982
11	-0.269	0.56	-0.316	-0.279

Standard thresholds

P-value	Threshold
0.001	3.647515
0.0005	4.76682
0.0001	6.987365