MotifERR3.H12INVIVO.0.PSM.A
Gene (human)ESRRG
(GeneCards)
Gene synonyms (human)ERR3, ERRG2, KIAA0832, NR3B3
Gene (mouse)Esrrg
Gene synonyms (mouse)Err3, Kiaa0832, Nr3b3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusbYSAAGGTCAh
GC content53.34%
Information content (bits; total / per base)12.964 / 1.179
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1007

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (19) 0.896 0.934 0.804 0.866 0.909 0.935 3.949 4.381 155.553 316.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.992 0.987 0.981 0.973 0.929 0.918
best 0.997 0.994 0.994 0.99 0.983 0.976
Methyl HT-SELEX, 2 experiments median 0.995 0.991 0.988 0.983 0.959 0.95
best 0.996 0.993 0.993 0.989 0.983 0.976
Non-Methyl HT-SELEX, 4 experiments median 0.865 0.864 0.794 0.798 0.738 0.742
best 0.997 0.994 0.994 0.99 0.982 0.976
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyER-like (NR3A) {2.1.1.2} (TFClass)
TFClass IDTFClass: 2.1.1.2.5
HGNCHGNC:3474
MGIMGI:1347056
EntrezGene (human)GeneID:2104
(SSTAR profile)
EntrezGene (mouse)GeneID:26381
(SSTAR profile)
UniProt ID (human)ERR3_HUMAN
UniProt ID (mouse)ERR3_MOUSE
UniProt AC (human)P62508
(TFClass)
UniProt AC (mouse)P62509
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
0180.0343.0273.0311.0
0236.0390.082.0499.0
0359.0753.0192.03.0
04922.011.072.02.0
05982.04.018.03.0
069.02.0981.015.0
072.02.01002.01.0
0864.07.0100.0836.0
092.0912.068.025.0
10933.011.060.03.0
11192.0442.0183.0190.0
PFM
ACGT
010.0790.3410.2710.309
020.0360.3870.0810.496
030.0590.7480.1910.003
040.9160.0110.0710.002
050.9750.0040.0180.003
060.0090.0020.9740.015
070.0020.0020.9950.001
080.0640.0070.0990.83
090.0020.9060.0680.025
100.9270.0110.060.003
110.1910.4390.1820.189
PWM
ACGT
01-1.1320.3070.0810.21
02-1.9050.435-1.1080.681
03-1.4291.091-0.269-3.982
041.293-2.991-1.235-4.219
051.356-3.79-2.553-3.982
06-3.162-4.2191.355-2.718
07-4.219-4.2191.376-4.531
08-1.35-3.369-0.9131.195
09-4.2191.282-1.291-2.25
101.305-2.991-1.413-3.982
11-0.2690.56-0.316-0.279
Standard thresholds
P-value Threshold
0.001 3.647515
0.0005 4.76682
0.0001 6.987365