Motif | ERR2.H12RSNP.0.PSM.D |
Gene (human) | ESRRB (GeneCards) |
Gene synonyms (human) | ERRB2, ESRL2, NR3B2 |
Gene (mouse) | Esrrb |
Gene synonyms (mouse) | Err-2, Err2, Nr3b2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | D |
Motif | ERR2.H12RSNP.0.PSM.D |
Gene (human) | ESRRB (GeneCards) |
Gene synonyms (human) | ERRB2, ESRL2, NR3B2 |
Gene (mouse) | Esrrb |
Gene synonyms (mouse) | Err-2, Err2, Nr3b2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | D |
Motif length | 12 |
Consensus | nbSAAGGTCAhn |
GC content | 48.32% |
Information content (bits; total / per base) | 13.7 / 1.142 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9986 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 34 (198) | 0.909 | 0.969 | 0.814 | 0.921 | 0.892 | 0.976 | 3.479 | 5.429 | 166.619 | 512.585 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 3 experiments | median | 0.964 | 0.955 | 0.795 | 0.803 | 0.657 | 0.685 |
best | 0.977 | 0.971 | 0.832 | 0.836 | 0.678 | 0.707 | |
Methyl HT-SELEX, 1 experiments | median | 0.964 | 0.955 | 0.795 | 0.803 | 0.657 | 0.685 |
best | 0.964 | 0.955 | 0.795 | 0.803 | 0.657 | 0.685 | |
Non-Methyl HT-SELEX, 2 experiments | median | 0.807 | 0.805 | 0.703 | 0.706 | 0.609 | 0.627 |
best | 0.977 | 0.971 | 0.832 | 0.836 | 0.678 | 0.707 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
TF family | Steroid hormone receptors {2.1.1} (TFClass) |
TF subfamily | ER-like (NR3A) {2.1.1.2} (TFClass) |
TFClass ID | TFClass: 2.1.1.2.4 |
HGNC | HGNC:3473 |
MGI | MGI:1346832 |
EntrezGene (human) | GeneID:2103 (SSTAR profile) |
EntrezGene (mouse) | GeneID:26380 (SSTAR profile) |
UniProt ID (human) | ERR2_HUMAN |
UniProt ID (mouse) | ERR2_MOUSE |
UniProt AC (human) | O95718 (TFClass) |
UniProt AC (mouse) | Q61539 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 34 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 1 |
PCM | ERR2.H12RSNP.0.PSM.D.pcm |
PWM | ERR2.H12RSNP.0.PSM.D.pwm |
PFM | ERR2.H12RSNP.0.PSM.D.pfm |
Alignment | ERR2.H12RSNP.0.PSM.D.words.tsv |
Threshold to P-value map | ERR2.H12RSNP.0.PSM.D.thr |
Motif in other formats | |
JASPAR format | ERR2.H12RSNP.0.PSM.D_jaspar_format.txt |
MEME format | ERR2.H12RSNP.0.PSM.D_meme_format.meme |
Transfac format | ERR2.H12RSNP.0.PSM.D_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1963.5 | 2185.5 | 2878.5 | 2958.5 |
02 | 1081.75 | 1923.75 | 1248.75 | 5731.75 |
03 | 567.0 | 6968.0 | 2163.0 | 288.0 |
04 | 9629.0 | 5.0 | 311.0 | 41.0 |
05 | 9976.0 | 3.0 | 6.0 | 1.0 |
06 | 0.0 | 0.0 | 9980.0 | 6.0 |
07 | 0.0 | 0.0 | 9986.0 | 0.0 |
08 | 141.0 | 4.0 | 229.0 | 9612.0 |
09 | 15.0 | 9492.0 | 99.0 | 380.0 |
10 | 7637.0 | 21.0 | 2318.0 | 10.0 |
11 | 2432.0 | 2445.0 | 738.0 | 4371.0 |
12 | 2445.5 | 2052.5 | 2844.5 | 2643.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.197 | 0.219 | 0.288 | 0.296 |
02 | 0.108 | 0.193 | 0.125 | 0.574 |
03 | 0.057 | 0.698 | 0.217 | 0.029 |
04 | 0.964 | 0.001 | 0.031 | 0.004 |
05 | 0.999 | 0.0 | 0.001 | 0.0 |
06 | 0.0 | 0.0 | 0.999 | 0.001 |
07 | 0.0 | 0.0 | 1.0 | 0.0 |
08 | 0.014 | 0.0 | 0.023 | 0.963 |
09 | 0.002 | 0.951 | 0.01 | 0.038 |
10 | 0.765 | 0.002 | 0.232 | 0.001 |
11 | 0.244 | 0.245 | 0.074 | 0.438 |
12 | 0.245 | 0.206 | 0.285 | 0.265 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.24 | -0.133 | 0.142 | 0.17 |
02 | -0.835 | -0.26 | -0.692 | 0.831 |
03 | -1.479 | 1.026 | -0.143 | -2.153 |
04 | 1.349 | -5.835 | -2.076 | -4.055 |
05 | 1.385 | -6.155 | -5.707 | -6.629 |
06 | -6.99 | -6.99 | 1.385 | -5.707 |
07 | -6.99 | -6.99 | 1.386 | -6.99 |
08 | -2.859 | -5.983 | -2.38 | 1.347 |
09 | -4.973 | 1.335 | -3.205 | -1.877 |
10 | 1.117 | -4.675 | -0.074 | -5.314 |
11 | -0.026 | -0.021 | -1.217 | 0.56 |
12 | -0.021 | -0.196 | 0.13 | 0.057 |
P-value | Threshold |
---|---|
0.001 | 2.21847 |
0.0005 | 3.75537 |
0.0001 | 6.904525 |