MotifERR2.H12INVITRO.0.PSM.A
Gene (human)ESRRB
(GeneCards)
Gene synonyms (human)ERRB2, ESRL2, NR3B2
Gene (mouse)Esrrb
Gene synonyms (mouse)Err-2, Err2, Nr3b2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusnbSAAGGTCAhn
GC content48.32%
Information content (bits; total / per base)13.7 / 1.142
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9986

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 34 (198) 0.909 0.969 0.814 0.921 0.892 0.976 3.479 5.429 166.619 512.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.964 0.955 0.795 0.803 0.657 0.685
best 0.977 0.971 0.832 0.836 0.678 0.707
Methyl HT-SELEX, 1 experiments median 0.964 0.955 0.795 0.803 0.657 0.685
best 0.964 0.955 0.795 0.803 0.657 0.685
Non-Methyl HT-SELEX, 2 experiments median 0.807 0.805 0.703 0.706 0.609 0.627
best 0.977 0.971 0.832 0.836 0.678 0.707
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyER-like (NR3A) {2.1.1.2} (TFClass)
TFClass IDTFClass: 2.1.1.2.4
HGNCHGNC:3473
MGIMGI:1346832
EntrezGene (human)GeneID:2103
(SSTAR profile)
EntrezGene (mouse)GeneID:26380
(SSTAR profile)
UniProt ID (human)ERR2_HUMAN
UniProt ID (mouse)ERR2_MOUSE
UniProt AC (human)O95718
(TFClass)
UniProt AC (mouse)Q61539
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 34 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
011963.52185.52878.52958.5
021081.751923.751248.755731.75
03567.06968.02163.0288.0
049629.05.0311.041.0
059976.03.06.01.0
060.00.09980.06.0
070.00.09986.00.0
08141.04.0229.09612.0
0915.09492.099.0380.0
107637.021.02318.010.0
112432.02445.0738.04371.0
122445.52052.52844.52643.5
PFM
ACGT
010.1970.2190.2880.296
020.1080.1930.1250.574
030.0570.6980.2170.029
040.9640.0010.0310.004
050.9990.00.0010.0
060.00.00.9990.001
070.00.01.00.0
080.0140.00.0230.963
090.0020.9510.010.038
100.7650.0020.2320.001
110.2440.2450.0740.438
120.2450.2060.2850.265
PWM
ACGT
01-0.24-0.1330.1420.17
02-0.835-0.26-0.6920.831
03-1.4791.026-0.143-2.153
041.349-5.835-2.076-4.055
051.385-6.155-5.707-6.629
06-6.99-6.991.385-5.707
07-6.99-6.991.386-6.99
08-2.859-5.983-2.381.347
09-4.9731.335-3.205-1.877
101.117-4.675-0.074-5.314
11-0.026-0.021-1.2170.56
12-0.021-0.1960.130.057
Standard thresholds
P-value Threshold
0.001 2.21847
0.0005 3.75537
0.0001 6.904525