MotifERG.H12CORE.0.P.B
Gene (human)ERG
(GeneCards)
Gene synonyms (human)
Gene (mouse)Erg
Gene synonyms (mouse)Erg-3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusRCCGGAAGYRvv
GC content58.74%
Information content (bits; total / per base)12.934 / 1.078
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 42 (221) 0.887 0.955 0.808 0.92 0.865 0.949 3.113 4.72 146.432 463.398
Mouse 11 (64) 0.924 0.973 0.847 0.939 0.917 0.966 3.634 4.67 270.048 466.824

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.98 0.97 0.883 0.884 0.709 0.742
best 0.998 0.997 0.994 0.99 0.987 0.981
Methyl HT-SELEX, 3 experiments median 0.775 0.753 0.62 0.635 0.544 0.573
best 0.812 0.77 0.674 0.665 0.589 0.6
Non-Methyl HT-SELEX, 7 experiments median 0.989 0.981 0.929 0.92 0.755 0.777
best 0.998 0.997 0.994 0.99 0.987 0.981

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 7.79 16.26 0.22 0.197

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.861 0.606 0.841 0.526
batch 2 0.901 0.69 0.87 0.656
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETS-like {3.5.2.1} (TFClass)
TFClass IDTFClass: 3.5.2.1.7
HGNCHGNC:3446
MGIMGI:95415
EntrezGene (human)GeneID:2078
(SSTAR profile)
EntrezGene (mouse)GeneID:13876
(SSTAR profile)
UniProt ID (human)ERG_HUMAN
UniProt ID (mouse)ERG_MOUSE
UniProt AC (human)P11308
(TFClass)
UniProt AC (mouse)P81270
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 42 human, 11 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
01560.074.0277.089.0
0264.0839.093.04.0
03262.0722.02.014.0
042.00.0996.02.0
054.01.0995.00.0
06998.00.02.00.0
07977.00.00.023.0
08221.07.0759.013.0
0925.0261.044.0670.0
10185.0125.0599.091.0
11331.0229.0355.085.0
12215.0364.0305.0116.0
PFM
ACGT
010.560.0740.2770.089
020.0640.8390.0930.004
030.2620.7220.0020.014
040.0020.00.9960.002
050.0040.0010.9950.0
060.9980.00.0020.0
070.9770.00.00.023
080.2210.0070.7590.013
090.0250.2610.0440.67
100.1850.1250.5990.091
110.3310.2290.3550.085
120.2150.3640.3050.116
PWM
ACGT
010.803-1.2010.102-1.02
02-1.3431.206-0.977-3.783
030.0471.056-4.213-2.773
04-4.213-4.9821.377-4.213
05-3.783-4.5251.376-4.982
061.379-4.982-4.213-4.982
071.358-4.982-4.982-2.32
08-0.122-3.3621.106-2.839
09-2.2430.043-1.7060.982
10-0.299-0.6860.87-0.999
110.279-0.0870.349-1.066
12-0.150.3740.198-0.76
Standard thresholds
P-value Threshold
0.001 3.458565
0.0005 4.71017
0.0001 7.260415