MotifEPAS1.H12CORE.0.P.B
Gene (human)EPAS1
(GeneCards)
Gene synonyms (human)BHLHE73, HIF2A, MOP2, PASD2
Gene (mouse)Epas1
Gene synonyms (mouse)Hif2a
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusdvvdACGTGMh
GC content59.69%
Information content (bits; total / per base)9.674 / 0.879
Data sourcesChIP-Seq
Aligned words1013

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 14 (90) 0.857 0.921 0.781 0.855 0.825 0.915 3.074 3.78 189.988 381.292

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 28.417 8.124 0.474 0.384
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-AHR {1.2.5.1} (TFClass)
TFClass IDTFClass: 1.2.5.1.7
HGNCHGNC:3374
MGIMGI:109169
EntrezGene (human)GeneID:2034
(SSTAR profile)
EntrezGene (mouse)GeneID:13819
(SSTAR profile)
UniProt ID (human)EPAS1_HUMAN
UniProt ID (mouse)EPAS1_MOUSE
UniProt AC (human)Q99814
(TFClass)
UniProt AC (mouse)P97481
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 14 human, 0 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01160.0130.0446.0277.0
02207.0195.0433.0178.0
03230.0233.0470.080.0
04164.0117.0263.0469.0
05798.030.0171.014.0
067.0966.06.034.0
0747.04.0959.03.0
081.02.01.01009.0
090.00.01013.00.0
10357.0511.050.095.0
11171.0490.0161.0191.0
PFM
ACGT
010.1580.1280.440.273
020.2040.1920.4270.176
030.2270.230.4640.079
040.1620.1150.260.463
050.7880.030.1690.014
060.0070.9540.0060.034
070.0460.0040.9470.003
080.0010.0020.0010.996
090.00.01.00.0
100.3520.5040.0490.094
110.1690.4840.1590.189
PWM
ACGT
01-0.455-0.660.5630.089
02-0.2-0.2590.534-0.35
03-0.096-0.0830.615-1.138
04-0.431-0.7640.0380.613
051.143-2.084-0.389-2.786
06-3.3741.334-3.496-1.965
07-1.655-3.7951.327-3.987
08-4.537-4.225-4.5371.377
09-4.993-4.9931.381-4.993
100.3410.699-1.595-0.969
11-0.3890.657-0.449-0.28
Standard thresholds
P-value Threshold
0.001 5.004535
0.0005 5.95634
0.0001 7.470485