Motif | EPAS1.H12CORE.0.P.B |
Gene (human) | EPAS1 (GeneCards) |
Gene synonyms (human) | BHLHE73, HIF2A, MOP2, PASD2 |
Gene (mouse) | Epas1 |
Gene synonyms (mouse) | Hif2a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | EPAS1.H12CORE.0.P.B |
Gene (human) | EPAS1 (GeneCards) |
Gene synonyms (human) | BHLHE73, HIF2A, MOP2, PASD2 |
Gene (mouse) | Epas1 |
Gene synonyms (mouse) | Hif2a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 11 |
Consensus | dvvdACGTGMh |
GC content | 59.69% |
Information content (bits; total / per base) | 9.674 / 0.879 |
Data sources | ChIP-Seq |
Aligned words | 1013 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 14 (90) | 0.857 | 0.921 | 0.781 | 0.855 | 0.825 | 0.915 | 3.074 | 3.78 | 189.988 | 381.292 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 28.417 | 8.124 | 0.474 | 0.384 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
TF family | PAS {1.2.5} (TFClass) |
TF subfamily | PAS-AHR {1.2.5.1} (TFClass) |
TFClass ID | TFClass: 1.2.5.1.7 |
HGNC | HGNC:3374 |
MGI | MGI:109169 |
EntrezGene (human) | GeneID:2034 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13819 (SSTAR profile) |
UniProt ID (human) | EPAS1_HUMAN |
UniProt ID (mouse) | EPAS1_MOUSE |
UniProt AC (human) | Q99814 (TFClass) |
UniProt AC (mouse) | P97481 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 14 human, 0 mouse |
HT-SELEX | 0 |
Methyl-HT-SELEX | 0 |
PCM | EPAS1.H12CORE.0.P.B.pcm |
PWM | EPAS1.H12CORE.0.P.B.pwm |
PFM | EPAS1.H12CORE.0.P.B.pfm |
Alignment | EPAS1.H12CORE.0.P.B.words.tsv |
Threshold to P-value map | EPAS1.H12CORE.0.P.B.thr |
Motif in other formats | |
JASPAR format | EPAS1.H12CORE.0.P.B_jaspar_format.txt |
MEME format | EPAS1.H12CORE.0.P.B_meme_format.meme |
Transfac format | EPAS1.H12CORE.0.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 160.0 | 130.0 | 446.0 | 277.0 |
02 | 207.0 | 195.0 | 433.0 | 178.0 |
03 | 230.0 | 233.0 | 470.0 | 80.0 |
04 | 164.0 | 117.0 | 263.0 | 469.0 |
05 | 798.0 | 30.0 | 171.0 | 14.0 |
06 | 7.0 | 966.0 | 6.0 | 34.0 |
07 | 47.0 | 4.0 | 959.0 | 3.0 |
08 | 1.0 | 2.0 | 1.0 | 1009.0 |
09 | 0.0 | 0.0 | 1013.0 | 0.0 |
10 | 357.0 | 511.0 | 50.0 | 95.0 |
11 | 171.0 | 490.0 | 161.0 | 191.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.158 | 0.128 | 0.44 | 0.273 |
02 | 0.204 | 0.192 | 0.427 | 0.176 |
03 | 0.227 | 0.23 | 0.464 | 0.079 |
04 | 0.162 | 0.115 | 0.26 | 0.463 |
05 | 0.788 | 0.03 | 0.169 | 0.014 |
06 | 0.007 | 0.954 | 0.006 | 0.034 |
07 | 0.046 | 0.004 | 0.947 | 0.003 |
08 | 0.001 | 0.002 | 0.001 | 0.996 |
09 | 0.0 | 0.0 | 1.0 | 0.0 |
10 | 0.352 | 0.504 | 0.049 | 0.094 |
11 | 0.169 | 0.484 | 0.159 | 0.189 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.455 | -0.66 | 0.563 | 0.089 |
02 | -0.2 | -0.259 | 0.534 | -0.35 |
03 | -0.096 | -0.083 | 0.615 | -1.138 |
04 | -0.431 | -0.764 | 0.038 | 0.613 |
05 | 1.143 | -2.084 | -0.389 | -2.786 |
06 | -3.374 | 1.334 | -3.496 | -1.965 |
07 | -1.655 | -3.795 | 1.327 | -3.987 |
08 | -4.537 | -4.225 | -4.537 | 1.377 |
09 | -4.993 | -4.993 | 1.381 | -4.993 |
10 | 0.341 | 0.699 | -1.595 | -0.969 |
11 | -0.389 | 0.657 | -0.449 | -0.28 |
P-value | Threshold |
---|---|
0.001 | 5.004535 |
0.0005 | 5.95634 |
0.0001 | 7.470485 |