MotifELF5.H12RSNP.1.S.B
Gene (human)ELF5
(GeneCards)
Gene synonyms (human)ESE2
Gene (mouse)Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusvnAbSCGGAAGTdn
GC content55.1%
Information content (bits; total / per base)17.195 / 1.228
Data sourcesHT-SELEX
Aligned words5718

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.795 0.797 0.74 0.743 0.862 0.882 3.402 3.501 217.481 223.319
Mouse 8 (45) 0.75 0.85 0.672 0.829 0.834 0.907 2.665 3.698 123.602 216.143

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 12 experiments median 0.986 0.974 0.92 0.908 0.792 0.79
best 0.999 0.999 0.997 0.996 0.946 0.928
Methyl HT-SELEX, 3 experiments median 0.987 0.973 0.972 0.956 0.935 0.915
best 0.988 0.975 0.976 0.963 0.946 0.928
Non-Methyl HT-SELEX, 9 experiments median 0.985 0.976 0.905 0.886 0.771 0.79
best 0.999 0.999 0.997 0.996 0.936 0.928

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.791 0.379 0.754 0.437
batch 2 0.776 0.556 0.777 0.573
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyEHF-like {3.5.2.4} (TFClass)
TFClass IDTFClass: 3.5.2.4.3
HGNCHGNC:3320
MGIMGI:1335079
EntrezGene (human)GeneID:2001
(SSTAR profile)
EntrezGene (mouse)GeneID:13711
(SSTAR profile)
UniProt ID (human)ELF5_HUMAN
UniProt ID (mouse)ELF5_MOUSE
UniProt AC (human)Q9UKW6
(TFClass)
UniProt AC (mouse)Q8VDK3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 8 mouse
HT-SELEX 9
Methyl-HT-SELEX 3
PCM
ACGT
01992.751523.752340.75860.75
022170.25934.251229.251384.25
035397.06.013.0302.0
04489.03380.0774.01075.0
05132.03450.02135.01.0
06338.05380.00.00.0
070.00.05718.00.0
080.00.05718.00.0
095718.00.00.00.0
105718.00.00.00.0
110.00.05718.00.0
120.03.00.05715.0
132730.0375.01802.0811.0
141243.01857.01753.0865.0
PFM
ACGT
010.1740.2660.4090.151
020.380.1630.2150.242
030.9440.0010.0020.053
040.0860.5910.1350.188
050.0230.6030.3730.0
060.0590.9410.00.0
070.00.01.00.0
080.00.01.00.0
091.00.00.00.0
101.00.00.00.0
110.00.01.00.0
120.00.0010.00.999
130.4770.0660.3150.142
140.2170.3250.3070.151
PWM
ACGT
01-0.3640.0640.493-0.506
020.417-0.425-0.151-0.032
031.327-5.167-4.548-1.549
04-1.070.86-0.612-0.285
05-2.3680.880.401-6.115
06-1.4371.324-6.495-6.495
07-6.495-6.4951.385-6.495
08-6.495-6.4951.385-6.495
091.385-6.495-6.495-6.495
101.385-6.495-6.495-6.495
11-6.495-6.4951.385-6.495
12-6.495-5.625-6.4951.385
130.646-1.3340.231-0.566
14-0.140.2610.204-0.501
Standard thresholds
P-value Threshold
0.001 -2.76293
0.0005 -0.29918
0.0001 3.77731