ELF5.H12RSNP.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H12RSNP.0.PSM.A
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	14
Consensus	vvWbvMGGAAGhdv
GC content	51.53%
Information content (bits; total / per base)	12.248 / 0.875
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	645

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.9	0.908	0.807	0.812	0.902	0.917	3.634	3.658	261.155	285.824
Mouse	8 (45)	0.915	0.955	0.835	0.911	0.923	0.962	3.868	4.595	199.076	338.022

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.976	0.961	0.934	0.914	0.812	0.807
Overall, 12 experiments	best	0.997	0.995	0.993	0.99	0.974	0.964
Methyl HT-SELEX, 3 experiments	median	0.991	0.985	0.984	0.974	0.965	0.951
Methyl HT-SELEX, 3 experiments	best	0.994	0.991	0.989	0.983	0.974	0.964
Non-Methyl HT-SELEX, 9 experiments	median	0.973	0.954	0.926	0.899	0.775	0.793
Non-Methyl HT-SELEX, 9 experiments	best	0.997	0.995	0.993	0.99	0.943	0.931

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.793	0.482	0.738	0.453
batch 2	0.842	0.717	0.808	0.61

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3

PCM	ELF5.H12RSNP.0.PSM.A.pcm
PWM	ELF5.H12RSNP.0.PSM.A.pwm
PFM	ELF5.H12RSNP.0.PSM.A.pfm
Alignment	ELF5.H12RSNP.0.PSM.A.words.tsv
Threshold to P-value map	ELF5.H12RSNP.0.PSM.A.thr
Motif in other formats
JASPAR format	ELF5.H12RSNP.0.PSM.A_jaspar_format.txt
MEME format	ELF5.H12RSNP.0.PSM.A_meme_format.meme
Transfac format	ELF5.H12RSNP.0.PSM.A_transfac_format.txt
Homer format	ELF5.H12RSNP.0.PSM.A_homer_format_0.001.txt ELF5.H12RSNP.0.PSM.A_homer_format_0.0005.txt ELF5.H12RSNP.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	155.0	149.0	291.0	50.0
02	306.0	108.0	147.0	84.0
03	500.0	20.0	55.0	70.0
04	81.0	207.0	235.0	122.0
05	137.0	250.0	247.0	11.0
06	447.0	168.0	28.0	2.0
07	1.0	1.0	642.0	1.0
08	2.0	2.0	639.0	2.0
09	641.0	2.0	1.0	1.0
10	638.0	0.0	4.0	3.0
11	112.0	11.0	521.0	1.0
12	111.0	104.0	56.0	374.0
13	190.0	90.0	261.0	104.0
14	169.0	152.0	262.0	62.0

PFM

	A	C	G	T
01	0.24	0.231	0.451	0.078
02	0.474	0.167	0.228	0.13
03	0.775	0.031	0.085	0.109
04	0.126	0.321	0.364	0.189
05	0.212	0.388	0.383	0.017
06	0.693	0.26	0.043	0.003
07	0.002	0.002	0.995	0.002
08	0.003	0.003	0.991	0.003
09	0.994	0.003	0.002	0.002
10	0.989	0.0	0.006	0.005
11	0.174	0.017	0.808	0.002
12	0.172	0.161	0.087	0.58
13	0.295	0.14	0.405	0.161
14	0.262	0.236	0.406	0.096

PWM

	A	C	G	T
01	-0.039	-0.078	0.586	-1.149
02	0.636	-0.396	-0.092	-0.643
03	1.125	-2.019	-1.057	-0.822
04	-0.679	0.248	0.374	-0.276
05	-0.161	0.435	0.423	-2.558
06	1.013	0.041	-1.705	-3.807
07	-4.131	-4.131	1.374	-4.131
08	-3.807	-3.807	1.369	-3.807
09	1.373	-3.807	-4.131	-4.131
10	1.368	-4.612	-3.367	-3.563
11	-0.36	-2.558	1.166	-4.131
12	-0.369	-0.433	-1.039	0.836
13	0.163	-0.575	0.478	-0.433
14	0.046	-0.058	0.482	-0.94

Standard thresholds

P-value	Threshold
0.001	3.89811
0.0005	5.08031
0.0001	7.41211