MotifELF5.H12INVIVO.1.S.B
Gene (human)ELF5
(GeneCards)
Gene synonyms (human)ESE2
Gene (mouse)Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusvnAbSCGGAAGTRn
GC content54.67%
Information content (bits; total / per base)17.348 / 1.239
Data sourcesHT-SELEX
Aligned words5544

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.795 0.797 0.739 0.744 0.862 0.881 3.421 3.494 218.721 223.174
Mouse 8 (45) 0.75 0.85 0.673 0.83 0.839 0.91 2.711 3.802 129.959 228.538

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 12 experiments median 0.985 0.975 0.919 0.906 0.791 0.789
best 0.999 0.999 0.997 0.996 0.946 0.928
Methyl HT-SELEX, 3 experiments median 0.988 0.974 0.971 0.956 0.934 0.915
best 0.989 0.977 0.977 0.964 0.946 0.928
Non-Methyl HT-SELEX, 9 experiments median 0.984 0.976 0.903 0.884 0.771 0.788
best 0.999 0.999 0.997 0.996 0.934 0.927

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.797 0.375 0.748 0.433
batch 2 0.78 0.562 0.774 0.57
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyEHF-like {3.5.2.4} (TFClass)
TFClass IDTFClass: 3.5.2.4.3
HGNCHGNC:3320
MGIMGI:1335079
EntrezGene (human)GeneID:2001
(SSTAR profile)
EntrezGene (mouse)GeneID:13711
(SSTAR profile)
UniProt ID (human)ELF5_HUMAN
UniProt ID (mouse)ELF5_MOUSE
UniProt AC (human)Q9UKW6
(TFClass)
UniProt AC (mouse)Q8VDK3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 8 mouse
HT-SELEX 9
Methyl-HT-SELEX 3
PCM
ACGT
01895.251332.252571.25745.25
022116.0878.01189.01361.0
035263.01.06.0274.0
04544.03067.0681.01252.0
05125.03229.02188.02.0
06409.05135.00.00.0
070.00.05544.00.0
080.00.05544.00.0
095544.00.00.00.0
105544.00.00.00.0
110.00.05544.00.0
120.01.00.05543.0
133013.0193.01702.0636.0
14990.01947.01683.0924.0
PFM
ACGT
010.1610.240.4640.134
020.3820.1580.2140.245
030.9490.00.0010.049
040.0980.5530.1230.226
050.0230.5820.3950.0
060.0740.9260.00.0
070.00.01.00.0
080.00.01.00.0
091.00.00.00.0
101.00.00.00.0
110.00.01.00.0
120.00.00.01.0
130.5430.0350.3070.115
140.1790.3510.3040.167
PWM
ACGT
01-0.436-0.0390.617-0.619
020.423-0.456-0.153-0.018
031.333-6.087-5.137-1.615
04-0.9330.793-0.709-0.102
05-2.390.8450.456-5.811
06-1.2171.309-6.468-6.468
07-6.468-6.4681.385-6.468
08-6.468-6.4681.385-6.468
091.385-6.468-6.468-6.468
101.385-6.468-6.468-6.468
11-6.468-6.4681.385-6.468
12-6.468-6.087-6.4681.385
130.776-1.9620.205-0.777
14-0.3360.3390.194-0.405
Standard thresholds
P-value Threshold
0.001 -2.98014
0.0005 -0.48729
0.0001 3.645215