ELF5.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H12INVITRO.1.S.B
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	dbSCGGAAGTdn
GC content	53.25%
Information content (bits; total / per base)	15.171 / 1.264
Data sources	HT-SELEX
Aligned words	487

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.792	0.793	0.733	0.739	0.832	0.854	2.99	3.091	184.994	196.013
Mouse	8 (45)	0.742	0.835	0.646	0.763	0.783	0.866	2.182	2.942	86.328	210.42

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.968	0.943	0.92	0.91	0.795	0.792
Overall, 12 experiments	best	0.999	0.998	0.996	0.994	0.941	0.924
Methyl HT-SELEX, 3 experiments	median	0.959	0.923	0.965	0.931	0.921	0.892
Methyl HT-SELEX, 3 experiments	best	0.977	0.948	0.978	0.955	0.936	0.914
Non-Methyl HT-SELEX, 9 experiments	median	0.984	0.976	0.91	0.898	0.771	0.788
Non-Methyl HT-SELEX, 9 experiments	best	0.999	0.998	0.996	0.994	0.941	0.924

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.791	0.368	0.756	0.441
batch 2	0.747	0.501	0.761	0.568

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3

PCM	ELF5.H12INVITRO.1.S.B.pcm
PWM	ELF5.H12INVITRO.1.S.B.pwm
PFM	ELF5.H12INVITRO.1.S.B.pfm
Alignment	ELF5.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	ELF5.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	ELF5.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	ELF5.H12INVITRO.1.S.B_meme_format.meme
Transfac format	ELF5.H12INVITRO.1.S.B_transfac_format.txt
Homer format	ELF5.H12INVITRO.1.S.B_homer_format_0.001.txt ELF5.H12INVITRO.1.S.B_homer_format_0.0005.txt ELF5.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	240.5	38.5	52.5	155.5
02	48.25	133.25	65.25	240.25
03	30.0	269.0	188.0	0.0
04	29.0	458.0	0.0	0.0
05	0.0	0.0	487.0	0.0
06	0.0	0.0	487.0	0.0
07	487.0	0.0	0.0	0.0
08	487.0	0.0	0.0	0.0
09	0.0	0.0	487.0	0.0
10	0.0	8.0	0.0	479.0
11	206.0	26.0	154.0	101.0
12	96.75	139.75	118.75	131.75

PFM

	A	C	G	T
01	0.494	0.079	0.108	0.319
02	0.099	0.274	0.134	0.493
03	0.062	0.552	0.386	0.0
04	0.06	0.94	0.0	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	1.0	0.0	0.0	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.016	0.0	0.984
11	0.423	0.053	0.316	0.207
12	0.199	0.287	0.244	0.271

PWM

	A	C	G	T
01	0.675	-1.125	-0.825	0.242
02	-0.907	0.089	-0.613	0.674
03	-1.363	0.786	0.43	-4.378
04	-1.395	1.316	-4.378	-4.378
05	-4.378	-4.378	1.377	-4.378
06	-4.378	-4.378	1.377	-4.378
07	1.377	-4.378	-4.378	-4.378
08	1.377	-4.378	-4.378	-4.378
09	-4.378	-4.378	1.377	-4.378
10	-4.378	-2.558	-4.378	1.36
11	0.521	-1.499	0.232	-0.184
12	-0.227	0.136	-0.025	0.078

Standard thresholds

P-value	Threshold
0.001	1.95842
0.0005	3.56767
0.0001	5.963915