ELF5.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H12INVITRO.0.PSM.A
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	ndnvMGGAAGbn
GC content	50.86%
Information content (bits; total / per base)	10.548 / 0.879
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9981

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.905	0.915	0.827	0.829	0.894	0.91	3.515	3.57	258.398	283.745
Mouse	8 (45)	0.918	0.959	0.842	0.914	0.9	0.944	3.245	4.518	192.125	318.357

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.985	0.976	0.946	0.93	0.835	0.829
Overall, 12 experiments	best	0.999	0.998	0.996	0.995	0.974	0.964
Methyl HT-SELEX, 3 experiments	median	0.992	0.985	0.986	0.977	0.969	0.956
Methyl HT-SELEX, 3 experiments	best	0.994	0.99	0.989	0.983	0.974	0.964
Non-Methyl HT-SELEX, 9 experiments	median	0.985	0.973	0.936	0.914	0.796	0.813
Non-Methyl HT-SELEX, 9 experiments	best	0.999	0.998	0.996	0.995	0.96	0.951

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.814	0.537	0.733	0.463
batch 2	0.847	0.691	0.797	0.604

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3

PCM	ELF5.H12INVITRO.0.PSM.A.pcm
PWM	ELF5.H12INVITRO.0.PSM.A.pwm
PFM	ELF5.H12INVITRO.0.PSM.A.pfm
Alignment	ELF5.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	ELF5.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	ELF5.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	ELF5.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	ELF5.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	ELF5.H12INVITRO.0.PSM.A_homer_format_0.001.txt ELF5.H12INVITRO.0.PSM.A_homer_format_0.0005.txt ELF5.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3304.25	1747.25	2726.25	2203.25
02	5343.75	902.75	1557.75	2176.75
03	1785.0	2959.0	2640.0	2597.0
04	2801.0	2888.0	3816.0	476.0
05	4516.0	4382.0	926.0	157.0
06	4.0	14.0	9957.0	6.0
07	4.0	8.0	9956.0	13.0
08	9973.0	2.0	2.0	4.0
09	9740.0	16.0	6.0	219.0
10	1193.0	358.0	8318.0	112.0
11	883.75	1571.75	1589.75	5935.75
12	3389.5	1457.5	3109.5	2024.5

PFM

	A	C	G	T
01	0.331	0.175	0.273	0.221
02	0.535	0.09	0.156	0.218
03	0.179	0.296	0.265	0.26
04	0.281	0.289	0.382	0.048
05	0.452	0.439	0.093	0.016
06	0.0	0.001	0.998	0.001
07	0.0	0.001	0.997	0.001
08	0.999	0.0	0.0	0.0
09	0.976	0.002	0.001	0.022
10	0.12	0.036	0.833	0.011
11	0.089	0.157	0.159	0.595
12	0.34	0.146	0.312	0.203

PWM

	A	C	G	T
01	0.281	-0.356	0.088	-0.124
02	0.761	-1.015	-0.471	-0.136
03	-0.335	0.17	0.056	0.04
04	0.115	0.146	0.424	-1.653
05	0.593	0.563	-0.99	-2.752
06	-5.982	-5.032	1.383	-5.707
07	-5.982	-5.491	1.383	-5.095
08	1.385	-6.364	-6.364	-5.982
09	1.361	-4.916	-5.707	-2.424
10	-0.737	-1.936	1.203	-3.084
11	-1.036	-0.462	-0.45	0.866
12	0.306	-0.537	0.22	-0.209

Standard thresholds

P-value	Threshold
0.001	4.65361
0.0005	5.851575
0.0001	7.670175