ELF5.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H12CORE.0.PSM.A
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	nvddWnvMGGAAGYdn
GC content	50.86%
Information content (bits; total / per base)	12.472 / 0.779
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	2488

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.906	0.915	0.82	0.829	0.904	0.919	3.735	3.756	260.086	268.745
Mouse	8 (45)	0.916	0.964	0.839	0.937	0.916	0.962	3.746	4.742	210.886	344.102

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.982	0.971	0.934	0.914	0.815	0.811
Overall, 12 experiments	best	0.998	0.997	0.995	0.992	0.972	0.961
Methyl HT-SELEX, 3 experiments	median	0.991	0.985	0.985	0.976	0.967	0.954
Methyl HT-SELEX, 3 experiments	best	0.994	0.99	0.988	0.982	0.972	0.961
Non-Methyl HT-SELEX, 9 experiments	median	0.981	0.967	0.933	0.903	0.762	0.784
Non-Methyl HT-SELEX, 9 experiments	best	0.998	0.997	0.995	0.992	0.948	0.936

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.804	0.534	0.732	0.468
batch 2	0.832	0.705	0.812	0.619

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3

PCM	ELF5.H12CORE.0.PSM.A.pcm
PWM	ELF5.H12CORE.0.PSM.A.pwm
PFM	ELF5.H12CORE.0.PSM.A.pfm
Alignment	ELF5.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	ELF5.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	ELF5.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	ELF5.H12CORE.0.PSM.A_meme_format.meme
Transfac format	ELF5.H12CORE.0.PSM.A_transfac_format.txt
Homer format	ELF5.H12CORE.0.PSM.A_homer_format_0.001.txt ELF5.H12CORE.0.PSM.A_homer_format_0.0005.txt ELF5.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	735.0	611.0	670.0	472.0
02	540.75	520.75	998.75	427.75
03	445.0	442.0	1141.0	460.0
04	1020.0	366.0	635.0	467.0
05	1717.0	76.0	268.0	427.0
06	400.0	750.0	776.0	562.0
07	696.0	742.0	994.0	56.0
08	1312.0	1052.0	120.0	4.0
09	0.0	0.0	2488.0	0.0
10	0.0	1.0	2483.0	4.0
11	2486.0	0.0	1.0	1.0
12	2469.0	4.0	0.0	15.0
13	207.0	31.0	2248.0	2.0
14	132.0	291.0	222.0	1843.0
15	948.75	280.75	762.75	495.75
16	702.0	619.0	654.0	513.0

PFM

	A	C	G	T
01	0.295	0.246	0.269	0.19
02	0.217	0.209	0.401	0.172
03	0.179	0.178	0.459	0.185
04	0.41	0.147	0.255	0.188
05	0.69	0.031	0.108	0.172
06	0.161	0.301	0.312	0.226
07	0.28	0.298	0.4	0.023
08	0.527	0.423	0.048	0.002
09	0.0	0.0	1.0	0.0
10	0.0	0.0	0.998	0.002
11	0.999	0.0	0.0	0.0
12	0.992	0.002	0.0	0.006
13	0.083	0.012	0.904	0.001
14	0.053	0.117	0.089	0.741
15	0.381	0.113	0.307	0.199
16	0.282	0.249	0.263	0.206

PWM

	A	C	G	T
01	0.166	-0.018	0.074	-0.275
02	-0.14	-0.177	0.472	-0.373
03	-0.334	-0.34	0.605	-0.301
04	0.493	-0.528	0.021	-0.286
05	1.013	-2.08	-0.838	-0.375
06	-0.44	0.187	0.221	-0.101
07	0.112	0.176	0.468	-2.376
08	0.745	0.524	-1.632	-4.652
09	-5.766	-5.766	1.384	-5.766
10	-5.766	-5.353	1.382	-4.652
11	1.383	-5.766	-5.353	-5.353
12	1.376	-4.652	-5.766	-3.606
13	-1.094	-2.941	1.283	-5.061
14	-1.539	-0.756	-1.025	1.084
15	0.421	-0.792	0.203	-0.226
16	0.121	-0.005	0.05	-0.192

Standard thresholds

P-value	Threshold
0.001	3.38281
0.0005	4.88241
0.0001	7.46296