MotifELF5.H12CORE.0.PSM.A
Gene (human)ELF5
(GeneCards)
Gene synonyms (human)ESE2
Gene (mouse)Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusnvddWnvMGGAAGYdn
GC content50.86%
Information content (bits; total / per base)12.472 / 0.779
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words2488

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.906 0.915 0.82 0.829 0.904 0.919 3.735 3.756 260.086 268.745
Mouse 8 (45) 0.916 0.964 0.839 0.937 0.916 0.962 3.746 4.742 210.886 344.102

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 12 experiments median 0.982 0.971 0.934 0.914 0.815 0.811
best 0.998 0.997 0.995 0.992 0.972 0.961
Methyl HT-SELEX, 3 experiments median 0.991 0.985 0.985 0.976 0.967 0.954
best 0.994 0.99 0.988 0.982 0.972 0.961
Non-Methyl HT-SELEX, 9 experiments median 0.981 0.967 0.933 0.903 0.762 0.784
best 0.998 0.997 0.995 0.992 0.948 0.936

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.804 0.534 0.732 0.468
batch 2 0.832 0.705 0.812 0.619
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyEHF-like {3.5.2.4} (TFClass)
TFClass IDTFClass: 3.5.2.4.3
HGNCHGNC:3320
MGIMGI:1335079
EntrezGene (human)GeneID:2001
(SSTAR profile)
EntrezGene (mouse)GeneID:13711
(SSTAR profile)
UniProt ID (human)ELF5_HUMAN
UniProt ID (mouse)ELF5_MOUSE
UniProt AC (human)Q9UKW6
(TFClass)
UniProt AC (mouse)Q8VDK3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 8 mouse
HT-SELEX 9
Methyl-HT-SELEX 3
PCM
ACGT
01735.0611.0670.0472.0
02540.75520.75998.75427.75
03445.0442.01141.0460.0
041020.0366.0635.0467.0
051717.076.0268.0427.0
06400.0750.0776.0562.0
07696.0742.0994.056.0
081312.01052.0120.04.0
090.00.02488.00.0
100.01.02483.04.0
112486.00.01.01.0
122469.04.00.015.0
13207.031.02248.02.0
14132.0291.0222.01843.0
15948.75280.75762.75495.75
16702.0619.0654.0513.0
PFM
ACGT
010.2950.2460.2690.19
020.2170.2090.4010.172
030.1790.1780.4590.185
040.410.1470.2550.188
050.690.0310.1080.172
060.1610.3010.3120.226
070.280.2980.40.023
080.5270.4230.0480.002
090.00.01.00.0
100.00.00.9980.002
110.9990.00.00.0
120.9920.0020.00.006
130.0830.0120.9040.001
140.0530.1170.0890.741
150.3810.1130.3070.199
160.2820.2490.2630.206
PWM
ACGT
010.166-0.0180.074-0.275
02-0.14-0.1770.472-0.373
03-0.334-0.340.605-0.301
040.493-0.5280.021-0.286
051.013-2.08-0.838-0.375
06-0.440.1870.221-0.101
070.1120.1760.468-2.376
080.7450.524-1.632-4.652
09-5.766-5.7661.384-5.766
10-5.766-5.3531.382-4.652
111.383-5.766-5.353-5.353
121.376-4.652-5.766-3.606
13-1.094-2.9411.283-5.061
14-1.539-0.756-1.0251.084
150.421-0.7920.203-0.226
160.121-0.0050.05-0.192
Standard thresholds
P-value Threshold
0.001 3.38281
0.0005 4.88241
0.0001 7.46296