MotifELF4.H12RSNP.0.PS.A
Gene (human)ELF4
(GeneCards)
Gene synonyms (human)ELFR, MEF
Gene (mouse)Elf4
Gene synonyms (mouse)Mef
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusdvSCGGAAGYR
GC content60.64%
Information content (bits; total / per base)13.331 / 1.212
Data sourcesChIP-Seq + HT-SELEX
Aligned words997

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.768 0.882 0.703 0.836 0.745 0.876 2.673 3.755 70.244 172.509
Mouse 3 (19) 0.969 0.979 0.925 0.954 0.961 0.972 4.491 4.688 242.432 369.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.997 0.994 0.995 0.991 0.988 0.982
best 0.998 0.997 0.998 0.996 0.995 0.993
Methyl HT-SELEX, 2 experiments median 0.996 0.993 0.994 0.99 0.985 0.978
best 0.997 0.994 0.995 0.992 0.99 0.985
Non-Methyl HT-SELEX, 2 experiments median 0.997 0.995 0.996 0.993 0.99 0.986
best 0.998 0.997 0.998 0.996 0.995 0.993

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.914 0.762 0.908 0.709
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyELF1-like {3.5.2.3} (TFClass)
TFClass IDTFClass: 3.5.2.3.3
HGNCHGNC:3319
MGIMGI:1928377
EntrezGene (human)GeneID:2000
(SSTAR profile)
EntrezGene (mouse)GeneID:56501
(SSTAR profile)
UniProt ID (human)ELF4_HUMAN
UniProt ID (mouse)ELF4_MOUSE
UniProt AC (human)Q99607
(TFClass)
UniProt AC (mouse)Q9Z2U4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01581.096.0114.0206.0
02191.0488.0214.0104.0
0354.0765.0170.08.0
04151.0841.04.01.0
052.00.0995.00.0
060.02.0995.00.0
07996.00.01.00.0
08993.00.01.03.0
0950.040.0905.02.0
1095.0229.034.0639.0
11158.0157.0599.083.0
PFM
ACGT
010.5830.0960.1140.207
020.1920.4890.2150.104
030.0540.7670.1710.008
040.1510.8440.0040.001
050.0020.00.9980.0
060.00.0020.9980.0
070.9990.00.0010.0
080.9960.00.0010.003
090.050.040.9080.002
100.0950.230.0340.641
110.1580.1570.6010.083
PWM
ACGT
010.842-0.943-0.774-0.189
02-0.2640.668-0.151-0.865
03-1.5051.117-0.379-3.251
04-0.4971.211-3.78-4.522
05-4.21-4.9791.379-4.979
06-4.979-4.211.379-4.979
071.38-4.979-4.522-4.979
081.377-4.979-4.522-3.972
09-1.579-1.7941.284-4.21
10-0.953-0.084-1.9490.937
11-0.452-0.4580.873-1.086
Standard thresholds
P-value Threshold
0.001 3.17172
0.0005 4.47641
0.0001 7.180585