MotifELF4.H12INVITRO.1.M.B
Gene (human)ELF4
(GeneCards)
Gene synonyms (human)ELFR, MEF
Gene (mouse)Elf4
Gene synonyms (mouse)Mef
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length15
ConsensusnvdWvSAGGAAGTRn
GC content48.62%
Information content (bits; total / per base)14.946 / 0.996
Data sourcesMethyl-HT-SELEX
Aligned words9772

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.749 0.85 0.631 0.763 0.769 0.869 2.671 3.437 61.495 129.921
Mouse 3 (19) 0.932 0.941 0.86 0.875 0.942 0.948 3.984 4.317 172.678 237.824

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.997 0.995 0.995 0.992 0.988 0.983
best 0.999 0.999 0.998 0.997 0.992 0.99
Methyl HT-SELEX, 2 experiments median 0.998 0.997 0.997 0.995 0.988 0.984
best 0.999 0.999 0.998 0.997 0.992 0.99
Non-Methyl HT-SELEX, 2 experiments median 0.994 0.99 0.992 0.987 0.984 0.977
best 0.997 0.994 0.996 0.992 0.992 0.988

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.921 0.702 0.894 0.675
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyELF1-like {3.5.2.3} (TFClass)
TFClass IDTFClass: 3.5.2.3.3
HGNCHGNC:3319
MGIMGI:1928377
EntrezGene (human)GeneID:2000
(SSTAR profile)
EntrezGene (mouse)GeneID:56501
(SSTAR profile)
UniProt ID (human)ELF4_HUMAN
UniProt ID (mouse)ELF4_MOUSE
UniProt AC (human)Q99607
(TFClass)
UniProt AC (mouse)Q9Z2U4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012544.752241.753218.751766.75
021958.01802.04460.01552.0
034634.0987.02504.01647.0
046566.0409.0805.01992.0
053746.02758.01797.01471.0
06482.07860.0975.0455.0
078014.01716.034.08.0
080.01.09769.02.0
090.00.09772.00.0
109772.00.00.00.0
119760.01.00.011.0
12478.037.09255.02.0
13110.0667.0255.08740.0
144417.0594.04063.0698.0
152838.02758.02526.01650.0
PFM
ACGT
010.260.2290.3290.181
020.20.1840.4560.159
030.4740.1010.2560.169
040.6720.0420.0820.204
050.3830.2820.1840.151
060.0490.8040.10.047
070.820.1760.0030.001
080.00.01.00.0
090.00.01.00.0
101.00.00.00.0
110.9990.00.00.001
120.0490.0040.9470.0
130.0110.0680.0260.894
140.4520.0610.4160.071
150.290.2820.2580.169
PWM
ACGT
010.041-0.0860.276-0.324
02-0.221-0.3040.601-0.453
030.64-0.9050.025-0.394
040.988-1.783-1.108-0.204
050.4270.121-0.307-0.507
06-1.6191.168-0.917-1.677
071.187-0.353-4.21-5.47
08-6.97-6.6091.385-6.344
09-6.97-6.971.386-6.97
101.386-6.97-6.97-6.97
111.384-6.609-6.97-5.214
12-1.628-4.1311.331-6.344
13-3.081-1.296-2.2521.274
140.592-1.4110.508-1.25
150.150.1210.033-0.392
Standard thresholds
P-value Threshold
0.001 1.24596
0.0005 3.01946
0.0001 6.49456