ELF4.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF4.H12INVITRO.0.PS.A
Gene (human)	ELF4 (GeneCards)
Gene synonyms (human)	ELFR, MEF
Gene (mouse)	Elf4
Gene synonyms (mouse)	Mef
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	ndnSCGGAAGTdn
GC content	54.97%
Information content (bits; total / per base)	14.593 / 1.123
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9672

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.769	0.871	0.69	0.823	0.749	0.868	2.654	3.628	69.155	155.721
Mouse	3 (19)	0.949	0.961	0.896	0.925	0.948	0.959	4.289	4.485	212.638	309.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.996	0.994	0.994	0.991	0.985	0.979
Overall, 4 experiments	best	0.999	0.998	0.999	0.998	0.997	0.995
Methyl HT-SELEX, 2 experiments	median	0.995	0.991	0.992	0.987	0.981	0.973
Methyl HT-SELEX, 2 experiments	best	0.996	0.993	0.994	0.99	0.986	0.98
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.996	0.997	0.995	0.99	0.987
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.999	0.998	0.997	0.995

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.898	0.705	0.898	0.699

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.3
HGNC	HGNC:3319
MGI	MGI:1928377
EntrezGene (human)	GeneID:2000 (SSTAR profile)
EntrezGene (mouse)	GeneID:56501 (SSTAR profile)
UniProt ID (human)	ELF4_HUMAN
UniProt ID (mouse)	ELF4_MOUSE
UniProt AC (human)	Q99607 (TFClass)
UniProt AC (mouse)	Q9Z2U4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ELF4.H12INVITRO.0.PS.A.pcm
PWM	ELF4.H12INVITRO.0.PS.A.pwm
PFM	ELF4.H12INVITRO.0.PS.A.pfm
Alignment	ELF4.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	ELF4.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	ELF4.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	ELF4.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	ELF4.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	ELF4.H12INVITRO.0.PS.A_homer_format_0.001.txt ELF4.H12INVITRO.0.PS.A_homer_format_0.0005.txt ELF4.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3245.0	1587.0	2752.0	2088.0
02	4660.5	812.5	1557.5	2641.5
03	2690.0	2147.0	1414.0	3421.0
04	606.0	5793.0	3228.0	45.0
05	408.0	9225.0	29.0	10.0
06	0.0	0.0	9671.0	1.0
07	0.0	0.0	9672.0	0.0
08	9672.0	0.0	0.0	0.0
09	9672.0	0.0	0.0	0.0
10	18.0	0.0	9654.0	0.0
11	69.0	605.0	136.0	8862.0
12	3193.5	907.5	4453.5	1117.5
13	2303.25	2739.25	2732.25	1897.25

PFM

	A	C	G	T
01	0.336	0.164	0.285	0.216
02	0.482	0.084	0.161	0.273
03	0.278	0.222	0.146	0.354
04	0.063	0.599	0.334	0.005
05	0.042	0.954	0.003	0.001
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.002	0.0	0.998	0.0
11	0.007	0.063	0.014	0.916
12	0.33	0.094	0.46	0.116
13	0.238	0.283	0.282	0.196

PWM

	A	C	G	T
01	0.294	-0.421	0.129	-0.147
02	0.656	-1.089	-0.439	0.088
03	0.107	-0.119	-0.536	0.347
04	-1.381	0.873	0.289	-3.935
05	-1.775	1.338	-4.348	-5.283
06	-6.961	-6.961	1.385	-6.599
07	-6.961	-6.961	1.386	-6.961
08	1.386	-6.961	-6.961	-6.961
09	1.386	-6.961	-6.961	-6.961
10	-4.781	-6.961	1.384	-6.961
11	-3.525	-1.383	-2.862	1.298
12	0.278	-0.978	0.61	-0.771
13	-0.049	0.125	0.122	-0.242

Standard thresholds

P-value	Threshold
0.001	0.52986
0.0005	2.26627
0.0001	6.273915