ELF3.H12RSNP.1.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF3.H12RSNP.1.PM.A
Gene (human)	ELF3 (GeneCards)
Gene synonyms (human)	ERT, ESX, JEN
Gene (mouse)	Elf3
Gene synonyms (mouse)	Ert, Esx, Jen
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	13
Consensus	hWbSAGGAAGTRv
GC content	43.56%
Information content (bits; total / per base)	15.144 / 1.165
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	9786

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (28)	0.903	0.96	0.829	0.924	0.911	0.965	3.71	4.689	256.849	406.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.974	0.965	0.798	0.81	0.646	0.684
Overall, 5 experiments	best	0.998	0.997	0.992	0.989	0.933	0.928
Methyl HT-SELEX, 1 experiments	median	0.998	0.997	0.992	0.989	0.881	0.892
Methyl HT-SELEX, 1 experiments	best	0.998	0.997	0.992	0.989	0.881	0.892
Non-Methyl HT-SELEX, 4 experiments	median	0.926	0.91	0.765	0.768	0.636	0.661
Non-Methyl HT-SELEX, 4 experiments	best	0.994	0.99	0.989	0.982	0.933	0.928

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.888	0.552	0.846	0.536

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.2
HGNC	HGNC:3318
MGI	MGI:1101781
EntrezGene (human)	GeneID:1999 (SSTAR profile)
EntrezGene (mouse)	GeneID:13710 (SSTAR profile)
UniProt ID (human)	ELF3_HUMAN
UniProt ID (mouse)	ELF3_MOUSE
UniProt AC (human)	P78545 (TFClass)
UniProt AC (mouse)	Q3UPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	1

PCM	ELF3.H12RSNP.1.PM.A.pcm
PWM	ELF3.H12RSNP.1.PM.A.pwm
PFM	ELF3.H12RSNP.1.PM.A.pfm
Alignment	ELF3.H12RSNP.1.PM.A.words.tsv
Threshold to P-value map	ELF3.H12RSNP.1.PM.A.thr
Motif in other formats
JASPAR format	ELF3.H12RSNP.1.PM.A_jaspar_format.txt
MEME format	ELF3.H12RSNP.1.PM.A_meme_format.meme
Transfac format	ELF3.H12RSNP.1.PM.A_transfac_format.txt
Homer format	ELF3.H12RSNP.1.PM.A_homer_format_0.001.txt ELF3.H12RSNP.1.PM.A_homer_format_0.0005.txt ELF3.H12RSNP.1.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3481.25	1532.25	1493.25	3279.25
02	7591.25	262.25	376.25	1556.25
03	1504.0	5237.0	1514.0	1531.0
04	1823.0	5986.0	1917.0	60.0
05	8809.0	928.0	38.0	11.0
06	0.0	1.0	9785.0	0.0
07	0.0	0.0	9786.0	0.0
08	9786.0	0.0	0.0	0.0
09	9782.0	3.0	0.0	1.0
10	1058.0	14.0	8711.0	3.0
11	82.0	456.0	187.0	9061.0
12	5776.25	363.25	2839.25	807.25
13	4272.5	2016.5	1964.5	1532.5

PFM

	A	C	G	T
01	0.356	0.157	0.153	0.335
02	0.776	0.027	0.038	0.159
03	0.154	0.535	0.155	0.156
04	0.186	0.612	0.196	0.006
05	0.9	0.095	0.004	0.001
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.108	0.001	0.89	0.0
11	0.008	0.047	0.019	0.926
12	0.59	0.037	0.29	0.082
13	0.437	0.206	0.201	0.157

PWM

	A	C	G	T
01	0.352	-0.467	-0.493	0.293
02	1.132	-2.225	-1.867	-0.452
03	-0.486	0.761	-0.479	-0.468
04	-0.294	0.894	-0.244	-3.671
05	1.28	-0.968	-4.107	-5.216
06	-6.972	-6.61	1.385	-6.972
07	-6.972	-6.972	1.386	-6.972
08	1.386	-6.972	-6.972	-6.972
09	1.385	-6.136	-6.972	-6.61
10	-0.837	-5.012	1.269	-6.136
11	-3.369	-1.676	-2.56	1.309
12	0.859	-1.902	0.149	-1.107
13	0.557	-0.193	-0.219	-0.467

Standard thresholds

P-value	Threshold
0.001	0.87071
0.0005	2.68402
0.0001	6.30185