ELF3.H12INVIVO.1.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF3.H12INVIVO.1.PM.A
Gene (human)	ELF3 (GeneCards)
Gene synonyms (human)	ERT, ESX, JEN
Gene (mouse)	Elf3
Gene synonyms (mouse)	Ert, Esx, Jen
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	13
Consensus	AbSMGGAAGYdvv
GC content	52.09%
Information content (bits; total / per base)	12.255 / 0.943
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	1003

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (28)	0.917	0.965	0.846	0.927	0.927	0.966	3.955	4.592	277.596	438.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.96	0.95	0.77	0.785	0.637	0.667
Overall, 5 experiments	best	0.996	0.993	0.989	0.984	0.936	0.93
Methyl HT-SELEX, 1 experiments	median	0.996	0.993	0.989	0.984	0.882	0.89
Methyl HT-SELEX, 1 experiments	best	0.996	0.993	0.989	0.984	0.882	0.89
Non-Methyl HT-SELEX, 4 experiments	median	0.93	0.913	0.758	0.763	0.633	0.659
Non-Methyl HT-SELEX, 4 experiments	best	0.993	0.987	0.989	0.982	0.936	0.93

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.872	0.54	0.831	0.537

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.2
HGNC	HGNC:3318
MGI	MGI:1101781
EntrezGene (human)	GeneID:1999 (SSTAR profile)
EntrezGene (mouse)	GeneID:13710 (SSTAR profile)
UniProt ID (human)	ELF3_HUMAN
UniProt ID (mouse)	ELF3_MOUSE
UniProt AC (human)	P78545 (TFClass)
UniProt AC (mouse)	Q3UPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	1

PCM	ELF3.H12INVIVO.1.PM.A.pcm
PWM	ELF3.H12INVIVO.1.PM.A.pwm
PFM	ELF3.H12INVIVO.1.PM.A.pfm
Alignment	ELF3.H12INVIVO.1.PM.A.words.tsv
Threshold to P-value map	ELF3.H12INVIVO.1.PM.A.thr
Motif in other formats
JASPAR format	ELF3.H12INVIVO.1.PM.A_jaspar_format.txt
MEME format	ELF3.H12INVIVO.1.PM.A_meme_format.meme
Transfac format	ELF3.H12INVIVO.1.PM.A_transfac_format.txt
Homer format	ELF3.H12INVIVO.1.PM.A_homer_format_0.001.txt ELF3.H12INVIVO.1.PM.A_homer_format_0.0005.txt ELF3.H12INVIVO.1.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	784.0	21.0	41.0	157.0
02	149.0	366.0	307.0	181.0
03	214.0	439.0	344.0	6.0
04	649.0	327.0	19.0	8.0
05	7.0	4.0	988.0	4.0
06	2.0	5.0	994.0	2.0
07	998.0	2.0	0.0	3.0
08	998.0	0.0	2.0	3.0
09	216.0	16.0	766.0	5.0
10	51.0	251.0	58.0	643.0
11	273.0	124.0	418.0	188.0
12	243.0	224.0	453.0	83.0
13	265.0	320.0	303.0	115.0

PFM

	A	C	G	T
01	0.782	0.021	0.041	0.157
02	0.149	0.365	0.306	0.18
03	0.213	0.438	0.343	0.006
04	0.647	0.326	0.019	0.008
05	0.007	0.004	0.985	0.004
06	0.002	0.005	0.991	0.002
07	0.995	0.002	0.0	0.003
08	0.995	0.0	0.002	0.003
09	0.215	0.016	0.764	0.005
10	0.051	0.25	0.058	0.641
11	0.272	0.124	0.417	0.187
12	0.242	0.223	0.452	0.083
13	0.264	0.319	0.302	0.115

PWM

	A	C	G	T
01	1.135	-2.408	-1.776	-0.464
02	-0.516	0.376	0.201	-0.323
03	-0.157	0.557	0.314	-3.487
04	0.947	0.264	-2.5	-3.256
05	-3.365	-3.786	1.366	-3.786
06	-4.216	-3.625	1.372	-4.216
07	1.376	-4.216	-4.985	-3.978
08	1.376	-4.985	-4.216	-3.978
09	-0.148	-2.656	1.112	-3.625
10	-1.566	0.001	-1.442	0.938
11	0.084	-0.697	0.508	-0.286
12	-0.031	-0.112	0.588	-1.092
13	0.055	0.242	0.188	-0.771

Standard thresholds

P-value	Threshold
0.001	3.76916
0.0005	4.94156
0.0001	7.43045