ELF3.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF3.H12INVITRO.0.S.B
Gene (human)	ELF3 (GeneCards)
Gene synonyms (human)	ERT, ESX, JEN
Gene (mouse)	Elf3
Gene synonyms (mouse)	Ert, Esx, Jen
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nWbSCGGAAGTdn
GC content	52.29%
Information content (bits; total / per base)	14.057 / 1.081
Data sources	HT-SELEX
Aligned words	9924

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (28)	0.922	0.966	0.857	0.929	0.913	0.95	3.511	3.877	269.261	399.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.984	0.981	0.809	0.824	0.652	0.692
Overall, 5 experiments	best	0.998	0.997	0.994	0.992	0.954	0.95
Methyl HT-SELEX, 1 experiments	median	0.993	0.989	0.987	0.98	0.891	0.895
Methyl HT-SELEX, 1 experiments	best	0.993	0.989	0.987	0.98	0.891	0.895
Non-Methyl HT-SELEX, 4 experiments	median	0.947	0.938	0.785	0.79	0.648	0.676
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.994	0.992	0.954	0.95

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.888	0.63	0.849	0.554

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.2
HGNC	HGNC:3318
MGI	MGI:1101781
EntrezGene (human)	GeneID:1999 (SSTAR profile)
EntrezGene (mouse)	GeneID:13710 (SSTAR profile)
UniProt ID (human)	ELF3_HUMAN
UniProt ID (mouse)	ELF3_MOUSE
UniProt AC (human)	P78545 (TFClass)
UniProt AC (mouse)	Q3UPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	1

PCM	ELF3.H12INVITRO.0.S.B.pcm
PWM	ELF3.H12INVITRO.0.S.B.pwm
PFM	ELF3.H12INVITRO.0.S.B.pfm
Alignment	ELF3.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	ELF3.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	ELF3.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	ELF3.H12INVITRO.0.S.B_meme_format.meme
Transfac format	ELF3.H12INVITRO.0.S.B_transfac_format.txt
Homer format	ELF3.H12INVITRO.0.S.B_homer_format_0.001.txt ELF3.H12INVITRO.0.S.B_homer_format_0.0005.txt ELF3.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2932.75	2163.75	1819.75	3007.75
02	6645.75	450.75	563.75	2263.75
03	1307.0	5215.0	1439.0	1963.0
04	1302.0	6079.0	2503.0	40.0
05	1095.0	8742.0	72.0	15.0
06	1.0	2.0	9916.0	5.0
07	1.0	0.0	9923.0	0.0
08	9923.0	0.0	0.0	1.0
09	9883.0	0.0	1.0	40.0
10	1244.0	34.0	8640.0	6.0
11	159.0	1038.0	260.0	8467.0
12	5023.0	650.0	3092.0	1159.0
13	3452.0	2675.0	2178.0	1619.0

PFM

	A	C	G	T
01	0.296	0.218	0.183	0.303
02	0.67	0.045	0.057	0.228
03	0.132	0.525	0.145	0.198
04	0.131	0.613	0.252	0.004
05	0.11	0.881	0.007	0.002
06	0.0	0.0	0.999	0.001
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	0.996	0.0	0.0	0.004
10	0.125	0.003	0.871	0.001
11	0.016	0.105	0.026	0.853
12	0.506	0.065	0.312	0.117
13	0.348	0.27	0.219	0.163

PWM

	A	C	G	T
01	0.167	-0.137	-0.31	0.192
02	0.985	-1.701	-1.479	-0.092
03	-0.64	0.742	-0.544	-0.234
04	-0.644	0.896	0.009	-4.073
05	-0.817	1.259	-3.509	-4.967
06	-6.623	-6.359	1.385	-5.829
07	-6.623	-6.984	1.385	-6.984
08	1.385	-6.984	-6.984	-6.623
09	1.381	-6.984	-6.623	-4.073
10	-0.689	-4.226	1.247	-5.701
11	-2.734	-0.87	-2.248	1.227
12	0.705	-1.337	0.22	-0.76
13	0.33	0.075	-0.13	-0.426

Standard thresholds

P-value	Threshold
0.001	1.88416
0.0005	3.59726
0.0001	6.89973