MotifELF3.H12CORE.1.PM.A
Gene (human)ELF3
(GeneCards)
Gene synonyms (human)ERT, ESX, JEN
Gene (mouse)Elf3
Gene synonyms (mouse)Ert, Esx, Jen
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensushWbSAGGAAGTRv
GC content43.56%
Information content (bits; total / per base)15.144 / 1.165
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words9786

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (28) 0.903 0.96 0.829 0.924 0.911 0.965 3.71 4.689 256.849 406.745

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.974 0.965 0.798 0.81 0.646 0.684
best 0.998 0.997 0.992 0.989 0.933 0.928
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.992 0.989 0.881 0.892
best 0.998 0.997 0.992 0.989 0.881 0.892
Non-Methyl HT-SELEX, 4 experiments median 0.926 0.91 0.765 0.768 0.636 0.661
best 0.994 0.99 0.989 0.982 0.933 0.928

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.888 0.552 0.846 0.536
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyEHF-like {3.5.2.4} (TFClass)
TFClass IDTFClass: 3.5.2.4.2
HGNCHGNC:3318
MGIMGI:1101781
EntrezGene (human)GeneID:1999
(SSTAR profile)
EntrezGene (mouse)GeneID:13710
(SSTAR profile)
UniProt ID (human)ELF3_HUMAN
UniProt ID (mouse)ELF3_MOUSE
UniProt AC (human)P78545
(TFClass)
UniProt AC (mouse)Q3UPW2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
013481.251532.251493.253279.25
027591.25262.25376.251556.25
031504.05237.01514.01531.0
041823.05986.01917.060.0
058809.0928.038.011.0
060.01.09785.00.0
070.00.09786.00.0
089786.00.00.00.0
099782.03.00.01.0
101058.014.08711.03.0
1182.0456.0187.09061.0
125776.25363.252839.25807.25
134272.52016.51964.51532.5
PFM
ACGT
010.3560.1570.1530.335
020.7760.0270.0380.159
030.1540.5350.1550.156
040.1860.6120.1960.006
050.90.0950.0040.001
060.00.01.00.0
070.00.01.00.0
081.00.00.00.0
091.00.00.00.0
100.1080.0010.890.0
110.0080.0470.0190.926
120.590.0370.290.082
130.4370.2060.2010.157
PWM
ACGT
010.352-0.467-0.4930.293
021.132-2.225-1.867-0.452
03-0.4860.761-0.479-0.468
04-0.2940.894-0.244-3.671
051.28-0.968-4.107-5.216
06-6.972-6.611.385-6.972
07-6.972-6.9721.386-6.972
081.386-6.972-6.972-6.972
091.385-6.136-6.972-6.61
10-0.837-5.0121.269-6.136
11-3.369-1.676-2.561.309
120.859-1.9020.149-1.107
130.557-0.193-0.219-0.467
Standard thresholds
P-value Threshold
0.001 0.87071
0.0005 2.68402
0.0001 6.30185