ELF3.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF3.H12CORE.0.S.B
Gene (human)	ELF3 (GeneCards)
Gene synonyms (human)	ERT, ESX, JEN
Gene (mouse)	Elf3
Gene synonyms (mouse)	Ert, Esx, Jen
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	dWvSCGGAAGTdn
GC content	50.72%
Information content (bits; total / per base)	13.342 / 1.026
Data sources	HT-SELEX
Aligned words	9166

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (28)	0.918	0.965	0.851	0.929	0.916	0.954	3.693	4.147	265.726	398.638

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.984	0.982	0.808	0.823	0.65	0.691
Overall, 5 experiments	best	0.998	0.997	0.994	0.992	0.949	0.946
Methyl HT-SELEX, 1 experiments	median	0.996	0.993	0.988	0.983	0.887	0.893
Methyl HT-SELEX, 1 experiments	best	0.996	0.993	0.988	0.983	0.887	0.893
Non-Methyl HT-SELEX, 4 experiments	median	0.945	0.937	0.779	0.786	0.644	0.673
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.994	0.992	0.949	0.946

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.903	0.635	0.858	0.571

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.2
HGNC	HGNC:3318
MGI	MGI:1101781
EntrezGene (human)	GeneID:1999 (SSTAR profile)
EntrezGene (mouse)	GeneID:13710 (SSTAR profile)
UniProt ID (human)	ELF3_HUMAN
UniProt ID (mouse)	ELF3_MOUSE
UniProt AC (human)	P78545 (TFClass)
UniProt AC (mouse)	Q3UPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	1

PCM	ELF3.H12CORE.0.S.B.pcm
PWM	ELF3.H12CORE.0.S.B.pwm
PFM	ELF3.H12CORE.0.S.B.pfm
Alignment	ELF3.H12CORE.0.S.B.words.tsv
Threshold to P-value map	ELF3.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	ELF3.H12CORE.0.S.B_jaspar_format.txt
MEME format	ELF3.H12CORE.0.S.B_meme_format.meme
Transfac format	ELF3.H12CORE.0.S.B_transfac_format.txt
Homer format	ELF3.H12CORE.0.S.B_homer_format_0.001.txt ELF3.H12CORE.0.S.B_homer_format_0.0005.txt ELF3.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3724.5	1368.5	1879.5	2193.5
02	6662.0	483.0	706.0	1315.0
03	1371.0	4602.0	2179.0	1014.0
04	1368.0	5683.0	1968.0	147.0
05	1744.0	7135.0	214.0	73.0
06	7.0	5.0	9146.0	8.0
07	0.0	1.0	9163.0	2.0
08	9164.0	0.0	2.0	0.0
09	9092.0	13.0	2.0	59.0
10	1417.0	101.0	7608.0	40.0
11	437.0	783.0	266.0	7680.0
12	4296.25	863.25	2408.25	1598.25
13	3594.0	1696.0	2160.0	1716.0

PFM

	A	C	G	T
01	0.406	0.149	0.205	0.239
02	0.727	0.053	0.077	0.143
03	0.15	0.502	0.238	0.111
04	0.149	0.62	0.215	0.016
05	0.19	0.778	0.023	0.008
06	0.001	0.001	0.998	0.001
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	0.992	0.001	0.0	0.006
10	0.155	0.011	0.83	0.004
11	0.048	0.085	0.029	0.838
12	0.469	0.094	0.263	0.174
13	0.392	0.185	0.236	0.187

PWM

	A	C	G	T
01	0.485	-0.515	-0.198	-0.044
02	1.067	-1.553	-1.175	-0.555
03	-0.513	0.697	-0.05	-0.814
04	-0.515	0.908	-0.152	-2.732
05	-0.273	1.135	-2.361	-3.417
06	-5.51	-5.753	1.383	-5.408
07	-6.913	-6.55	1.385	-6.284
08	1.385	-6.913	-6.284	-6.913
09	1.377	-5.011	-6.284	-3.622
10	-0.48	-3.101	1.199	-3.994
11	-1.653	-1.072	-2.146	1.209
12	0.628	-0.975	0.05	-0.36
13	0.45	-0.301	-0.059	-0.289

Standard thresholds

P-value	Threshold
0.001	2.930465
0.0005	4.42041
0.0001	7.148055