ELF2.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF2.H12INVIVO.0.PS.A
Gene (human)	ELF2 (GeneCards)
Gene synonyms (human)	NERF
Gene (mouse)	Elf2
Gene synonyms (mouse)	Nerf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	SCGGAAGYR
GC content	64.43%
Information content (bits; total / per base)	12.595 / 1.399
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.883	0.936	0.827	0.887	0.861	0.943	3.177	4.007	40.77	89.328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.995	0.991	0.992	0.987	0.983	0.976
Overall, 5 experiments	best	0.999	0.998	0.998	0.997	0.997	0.996
Methyl HT-SELEX, 2 experiments	median	0.994	0.989	0.988	0.982	0.974	0.964
Methyl HT-SELEX, 2 experiments	best	0.995	0.991	0.992	0.987	0.983	0.976
Non-Methyl HT-SELEX, 3 experiments	median	0.998	0.997	0.996	0.994	0.993	0.989
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.998	0.997	0.997	0.996

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.97	0.714	0.96	0.601
batch 2	0.871	0.695	0.897	0.659

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.2
HGNC	HGNC:3317
MGI	MGI:1916507
EntrezGene (human)	GeneID:1998 (SSTAR profile)
EntrezGene (mouse)	GeneID:69257 (SSTAR profile)
UniProt ID (human)	ELF2_HUMAN
UniProt ID (mouse)	ELF2_MOUSE
UniProt AC (human)	Q15723 (TFClass)
UniProt AC (mouse)	Q9JHC9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	2

PCM	ELF2.H12INVIVO.0.PS.A.pcm
PWM	ELF2.H12INVIVO.0.PS.A.pwm
PFM	ELF2.H12INVIVO.0.PS.A.pfm
Alignment	ELF2.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	ELF2.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	ELF2.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	ELF2.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	ELF2.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	ELF2.H12INVIVO.0.PS.A_homer_format_0.001.txt ELF2.H12INVIVO.0.PS.A_homer_format_0.0005.txt ELF2.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	40.0	680.0	265.0	15.0
02	126.0	857.0	9.0	8.0
03	1.0	3.0	992.0	4.0
04	4.0	1.0	995.0	0.0
05	994.0	2.0	2.0	2.0
06	994.0	1.0	1.0	4.0
07	45.0	7.0	946.0	2.0
08	118.0	227.0	38.0	617.0
09	152.0	138.0	635.0	75.0

PFM

	A	C	G	T
01	0.04	0.68	0.265	0.015
02	0.126	0.857	0.009	0.008
03	0.001	0.003	0.992	0.004
04	0.004	0.001	0.995	0.0
05	0.994	0.002	0.002	0.002
06	0.994	0.001	0.001	0.004
07	0.045	0.007	0.946	0.002
08	0.118	0.227	0.038	0.617
09	0.152	0.138	0.635	0.075

PWM

	A	C	G	T
01	-1.797	0.996	0.058	-2.711
02	-0.678	1.227	-3.156	-3.253
03	-4.525	-3.975	1.373	-3.783
04	-3.783	-4.525	1.376	-4.982
05	1.375	-4.213	-4.213	-4.213
06	1.375	-4.525	-4.525	-3.783
07	-1.684	-3.362	1.326	-4.213
08	-0.743	-0.096	-1.846	0.899
09	-0.493	-0.589	0.928	-1.188

Standard thresholds

P-value	Threshold
0.001	3.550495
0.0005	4.754135
0.0001	7.383645