ELF2.H12INVITRO.1.M.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF2.H12INVITRO.1.M.B
Gene (human)	ELF2 (GeneCards)
Gene synonyms (human)	NERF
Gene (mouse)	Elf2
Gene synonyms (mouse)	Nerf
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	15
Consensus	nWAMCMGGAAGTRvn
GC content	47.37%
Information content (bits; total / per base)	17.117 / 1.141
Data sources	Methyl-HT-SELEX
Aligned words	2499

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.835	0.885	0.751	0.776	0.861	0.914	3.356	4.015	23.824	57.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.999	0.997	0.997	0.995	0.989	0.985
Overall, 5 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.999	0.998	0.995	0.994	0.916	0.925
Methyl HT-SELEX, 2 experiments	best	1.0	0.999	0.997	0.995	0.989	0.985
Non-Methyl HT-SELEX, 3 experiments	median	0.998	0.997	0.997	0.995	0.992	0.988
Non-Methyl HT-SELEX, 3 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.933	0.605	0.936	0.577
batch 2	0.878	0.679	0.877	0.63

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.2
HGNC	HGNC:3317
MGI	MGI:1916507
EntrezGene (human)	GeneID:1998 (SSTAR profile)
EntrezGene (mouse)	GeneID:69257 (SSTAR profile)
UniProt ID (human)	ELF2_HUMAN
UniProt ID (mouse)	ELF2_MOUSE
UniProt AC (human)	Q15723 (TFClass)
UniProt AC (mouse)	Q9JHC9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	2

PCM	ELF2.H12INVITRO.1.M.B.pcm
PWM	ELF2.H12INVITRO.1.M.B.pwm
PFM	ELF2.H12INVITRO.1.M.B.pfm
Alignment	ELF2.H12INVITRO.1.M.B.words.tsv
Threshold to P-value map	ELF2.H12INVITRO.1.M.B.thr
Motif in other formats
JASPAR format	ELF2.H12INVITRO.1.M.B_jaspar_format.txt
MEME format	ELF2.H12INVITRO.1.M.B_meme_format.meme
Transfac format	ELF2.H12INVITRO.1.M.B_transfac_format.txt
Homer format	ELF2.H12INVITRO.1.M.B_homer_format_0.001.txt ELF2.H12INVITRO.1.M.B_homer_format_0.0005.txt ELF2.H12INVITRO.1.M.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	839.0	493.0	774.0	393.0
02	1720.75	163.75	256.75	357.75
03	1961.0	46.0	71.0	421.0
04	540.0	1556.0	118.0	285.0
05	39.0	2363.0	68.0	29.0
06	1299.0	1188.0	7.0	5.0
07	2.0	7.0	2490.0	0.0
08	1.0	0.0	2498.0	0.0
09	2497.0	0.0	1.0	1.0
10	2495.0	2.0	0.0	2.0
11	27.0	5.0	2461.0	6.0
12	13.0	56.0	15.0	2415.0
13	1326.0	80.0	971.0	122.0
14	1007.25	537.25	535.25	419.25
15	763.25	522.25	472.25	741.25

PFM

	A	C	G	T
01	0.336	0.197	0.31	0.157
02	0.689	0.066	0.103	0.143
03	0.785	0.018	0.028	0.168
04	0.216	0.623	0.047	0.114
05	0.016	0.946	0.027	0.012
06	0.52	0.475	0.003	0.002
07	0.001	0.003	0.996	0.0
08	0.0	0.0	1.0	0.0
09	0.999	0.0	0.0	0.0
10	0.998	0.001	0.0	0.001
11	0.011	0.002	0.985	0.002
12	0.005	0.022	0.006	0.966
13	0.531	0.032	0.389	0.049
14	0.403	0.215	0.214	0.168
15	0.305	0.209	0.189	0.297

PWM

	A	C	G	T
01	0.294	-0.236	0.214	-0.462
02	1.011	-1.33	-0.885	-0.555
03	1.142	-2.57	-2.151	-0.393
04	-0.145	0.911	-1.653	-0.781
05	-2.728	1.328	-2.193	-3.008
06	0.73	0.641	-4.248	-4.501
07	-5.065	-4.248	1.38	-5.77
08	-5.357	-5.77	1.384	-5.77
09	1.383	-5.77	-5.357	-5.357
10	1.382	-5.065	-5.77	-5.065
11	-3.075	-4.501	1.369	-4.367
12	-3.735	-2.381	-3.61	1.35
13	0.751	-2.034	0.44	-1.621
14	0.476	-0.15	-0.154	-0.397
15	0.2	-0.179	-0.279	0.17

Standard thresholds

P-value	Threshold
0.001	0.26246
0.0005	1.87261
0.0001	5.26041