ELF1.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF1.H12CORE.0.PSM.A
Gene (human)	ELF1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Elf1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	vdvSCGGAAGYvv
GC content	60.05%
Information content (bits; total / per base)	13.095 / 1.007
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	28 (179)	0.958	0.986	0.913	0.97	0.948	0.976	4.457	5.092	363.161	681.0
Mouse	5 (33)	0.964	0.982	0.928	0.958	0.946	0.971	4.323	4.764	375.027	460.481

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.999	0.998	0.997	0.996	0.961	0.961
Overall, 5 experiments	best	1.0	0.999	0.999	0.999	0.998	0.997
Methyl HT-SELEX, 2 experiments	median	0.994	0.99	0.992	0.986	0.958	0.954
Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.997	0.996	0.975	0.963
Non-Methyl HT-SELEX, 3 experiments	median	0.999	0.998	0.998	0.996	0.961	0.961
Non-Methyl HT-SELEX, 3 experiments	best	1.0	0.999	0.999	0.999	0.998	0.997

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	8.706	40.11	0.299	0.208

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.999	0.921	0.972	0.577
batch 2	0.835	0.65	0.818	0.606

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.1
HGNC	HGNC:3316
MGI	MGI:107180
EntrezGene (human)	GeneID:1997 (SSTAR profile)
EntrezGene (mouse)	GeneID:13709 (SSTAR profile)
UniProt ID (human)	ELF1_HUMAN
UniProt ID (mouse)	ELF1_MOUSE
UniProt AC (human)	P32519 (TFClass)
UniProt AC (mouse)	Q60775 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	28 human, 5 mouse
HT-SELEX	3
Methyl-HT-SELEX	2

PCM	ELF1.H12CORE.0.PSM.A.pcm
PWM	ELF1.H12CORE.0.PSM.A.pwm
PFM	ELF1.H12CORE.0.PSM.A.pfm
Alignment	ELF1.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	ELF1.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	ELF1.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	ELF1.H12CORE.0.PSM.A_meme_format.meme
Transfac format	ELF1.H12CORE.0.PSM.A_transfac_format.txt
Homer format	ELF1.H12CORE.0.PSM.A_homer_format_0.001.txt ELF1.H12CORE.0.PSM.A_homer_format_0.0005.txt ELF1.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	426.0	152.0	294.0	124.0
02	550.0	89.0	152.0	205.0
03	185.0	427.0	252.0	132.0
04	61.0	689.0	239.0	7.0
05	162.0	827.0	6.0	1.0
06	1.0	0.0	995.0	0.0
07	0.0	1.0	995.0	0.0
08	990.0	0.0	2.0	4.0
09	990.0	0.0	2.0	4.0
10	67.0	51.0	877.0	1.0
11	102.0	251.0	34.0	609.0
12	173.0	154.0	577.0	92.0
13	200.0	299.0	410.0	87.0

PFM

	A	C	G	T
01	0.428	0.153	0.295	0.124
02	0.552	0.089	0.153	0.206
03	0.186	0.429	0.253	0.133
04	0.061	0.692	0.24	0.007
05	0.163	0.83	0.006	0.001
06	0.001	0.0	0.999	0.0
07	0.0	0.001	0.999	0.0
08	0.994	0.0	0.002	0.004
09	0.994	0.0	0.002	0.004
10	0.067	0.051	0.881	0.001
11	0.102	0.252	0.034	0.611
12	0.174	0.155	0.579	0.092
13	0.201	0.3	0.412	0.087

PWM

	A	C	G	T
01	0.534	-0.489	0.165	-0.69
02	0.789	-1.017	-0.489	-0.193
03	-0.295	0.536	0.012	-0.629
04	-1.386	1.013	-0.041	-3.358
05	-0.426	1.196	-3.48	-4.522
06	-4.522	-4.979	1.38	-4.979
07	-4.979	-4.522	1.38	-4.979
08	1.375	-4.979	-4.209	-3.779
09	1.375	-4.979	-4.209	-3.779
10	-1.294	-1.559	1.254	-4.522
11	-0.883	0.008	-1.948	0.89
12	-0.361	-0.476	0.836	-0.984
13	-0.217	0.182	0.496	-1.039

Standard thresholds

P-value	Threshold
0.001	3.31426
0.0005	4.624965
0.0001	7.27206