EGR4.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	EGR4.H12CORE.0.S.B
Gene (human)	EGR4 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Egr4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	RKGGGCGKdn
GC content	66.72%
Information content (bits; total / per base)	10.249 / 1.025
Data sources	HT-SELEX
Aligned words	3987

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 5 experiments	median	0.667	0.629	0.585	0.585	0.547	0.556
Non-Methyl HT-SELEX, 5 experiments	best	0.988	0.979	0.983	0.972	0.954	0.941

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	EGR {2.3.1.3} (TFClass)
TFClass ID	TFClass: 2.3.1.3.4
HGNC	HGNC:3241
MGI	MGI:99252
EntrezGene (human)	GeneID:1961 (SSTAR profile)
EntrezGene (mouse)	GeneID:13656 (SSTAR profile)
UniProt ID (human)	EGR4_HUMAN
UniProt ID (mouse)	EGR4_MOUSE
UniProt AC (human)	Q05215 (TFClass)
UniProt AC (mouse)	Q9WUF2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	0

PCM	EGR4.H12CORE.0.S.B.pcm
PWM	EGR4.H12CORE.0.S.B.pwm
PFM	EGR4.H12CORE.0.S.B.pfm
Alignment	EGR4.H12CORE.0.S.B.words.tsv
Threshold to P-value map	EGR4.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	EGR4.H12CORE.0.S.B_jaspar_format.txt
MEME format	EGR4.H12CORE.0.S.B_meme_format.meme
Transfac format	EGR4.H12CORE.0.S.B_transfac_format.txt
Homer format	EGR4.H12CORE.0.S.B_homer_format_0.001.txt EGR4.H12CORE.0.S.B_homer_format_0.0005.txt EGR4.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	559.75	305.75	2679.75	441.75
02	412.75	127.75	814.75	2631.75
03	617.0	0.0	3338.0	32.0
04	294.0	389.0	3304.0	0.0
05	4.0	0.0	3983.0	0.0
06	34.0	3727.0	0.0	226.0
07	154.0	0.0	3833.0	0.0
08	206.0	11.0	959.0	2811.0
09	1369.25	202.25	1294.25	1121.25
10	1056.25	544.25	1090.25	1296.25

PFM

	A	C	G	T
01	0.14	0.077	0.672	0.111
02	0.104	0.032	0.204	0.66
03	0.155	0.0	0.837	0.008
04	0.074	0.098	0.829	0.0
05	0.001	0.0	0.999	0.0
06	0.009	0.935	0.0	0.057
07	0.039	0.0	0.961	0.0
08	0.052	0.003	0.241	0.705
09	0.343	0.051	0.325	0.281
10	0.265	0.137	0.273	0.325

PWM

	A	C	G	T
01	-0.575	-1.177	0.988	-0.811
02	-0.879	-2.04	-0.201	0.97
03	-0.478	-6.178	1.207	-3.378
04	-1.216	-0.938	1.197	-6.178
05	-5.103	-6.178	1.384	-6.178
06	-3.321	1.317	-6.178	-1.477
07	-1.856	-6.178	1.345	-6.178
08	-1.569	-4.336	-0.039	1.035
09	0.317	-1.587	0.261	0.117
10	0.058	-0.603	0.089	0.262

Standard thresholds

P-value	Threshold
0.001	4.812005
0.0005	5.722385
0.0001	7.44758