Motif | EGR3.H12RSNP.0.PSM.A |
Gene (human) | EGR3 (GeneCards) |
Gene synonyms (human) | PILOT |
Gene (mouse) | Egr3 |
Gene synonyms (mouse) | Egr-3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | EGR3.H12RSNP.0.PSM.A |
Gene (human) | EGR3 (GeneCards) |
Gene synonyms (human) | PILOT |
Gene (mouse) | Egr3 |
Gene synonyms (mouse) | Egr-3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 13 |
Consensus | bRCGTGGGCGKdn |
GC content | 70.42% |
Information content (bits; total / per base) | 13.392 / 1.03 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 5943 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (5) | 0.851 | 0.901 | 0.7 | 0.783 | 0.841 | 0.847 | 2.671 | 2.695 | 110.252 | 171.046 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.644 | 0.665 | 0.566 | 0.583 | 0.537 | 0.548 |
best | 0.999 | 0.998 | 0.999 | 0.998 | 0.997 | 0.996 | |
Methyl HT-SELEX, 1 experiments | median | 0.99 | 0.987 | 0.815 | 0.835 | 0.642 | 0.693 |
best | 0.99 | 0.987 | 0.815 | 0.835 | 0.642 | 0.693 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.616 | 0.634 | 0.555 | 0.567 | 0.533 | 0.539 |
best | 0.999 | 0.998 | 0.999 | 0.998 | 0.997 | 0.996 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.847 | 0.491 | 0.846 | 0.519 |
batch 2 | 0.86 | 0.743 | 0.835 | 0.555 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | C2H2 zinc finger factors {2.3} (TFClass) |
TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
TF subfamily | EGR {2.3.1.3} (TFClass) |
TFClass ID | TFClass: 2.3.1.3.3 |
HGNC | HGNC:3240 |
MGI | MGI:1306780 |
EntrezGene (human) | GeneID:1960 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13655 (SSTAR profile) |
UniProt ID (human) | EGR3_HUMAN |
UniProt ID (mouse) | EGR3_MOUSE |
UniProt AC (human) | Q06889 (TFClass) |
UniProt AC (mouse) | P43300 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 1 |
PCM | EGR3.H12RSNP.0.PSM.A.pcm |
PWM | EGR3.H12RSNP.0.PSM.A.pwm |
PFM | EGR3.H12RSNP.0.PSM.A.pfm |
Alignment | EGR3.H12RSNP.0.PSM.A.words.tsv |
Threshold to P-value map | EGR3.H12RSNP.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | EGR3.H12RSNP.0.PSM.A_jaspar_format.txt |
MEME format | EGR3.H12RSNP.0.PSM.A_meme_format.meme |
Transfac format | EGR3.H12RSNP.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 872.75 | 1160.75 | 908.75 | 3000.75 |
02 | 852.25 | 707.25 | 3634.25 | 749.25 |
03 | 379.0 | 4833.0 | 417.0 | 314.0 |
04 | 244.0 | 85.0 | 5439.0 | 175.0 |
05 | 167.0 | 22.0 | 971.0 | 4783.0 |
06 | 247.0 | 7.0 | 5640.0 | 49.0 |
07 | 20.0 | 19.0 | 5702.0 | 202.0 |
08 | 20.0 | 2.0 | 5885.0 | 36.0 |
09 | 304.0 | 5306.0 | 108.0 | 225.0 |
10 | 160.0 | 61.0 | 5595.0 | 127.0 |
11 | 302.0 | 127.0 | 2020.0 | 3494.0 |
12 | 1858.75 | 540.75 | 2163.75 | 1379.75 |
13 | 1542.75 | 899.75 | 2151.75 | 1348.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.147 | 0.195 | 0.153 | 0.505 |
02 | 0.143 | 0.119 | 0.612 | 0.126 |
03 | 0.064 | 0.813 | 0.07 | 0.053 |
04 | 0.041 | 0.014 | 0.915 | 0.029 |
05 | 0.028 | 0.004 | 0.163 | 0.805 |
06 | 0.042 | 0.001 | 0.949 | 0.008 |
07 | 0.003 | 0.003 | 0.959 | 0.034 |
08 | 0.003 | 0.0 | 0.99 | 0.006 |
09 | 0.051 | 0.893 | 0.018 | 0.038 |
10 | 0.027 | 0.01 | 0.941 | 0.021 |
11 | 0.051 | 0.021 | 0.34 | 0.588 |
12 | 0.313 | 0.091 | 0.364 | 0.232 |
13 | 0.26 | 0.151 | 0.362 | 0.227 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.531 | -0.246 | -0.491 | 0.702 |
02 | -0.555 | -0.741 | 0.894 | -0.683 |
03 | -1.362 | 1.179 | -1.267 | -1.549 |
04 | -1.799 | -2.837 | 1.297 | -2.128 |
05 | -2.174 | -4.12 | -0.425 | 1.168 |
06 | -1.787 | -5.089 | 1.333 | -3.37 |
07 | -4.206 | -4.252 | 1.344 | -1.986 |
08 | -4.206 | -5.877 | 1.375 | -3.663 |
09 | -1.581 | 1.272 | -2.603 | -1.879 |
10 | -2.216 | -3.159 | 1.325 | -2.444 |
11 | -1.588 | -2.444 | 0.307 | 0.854 |
12 | 0.224 | -1.008 | 0.375 | -0.074 |
13 | 0.038 | -0.501 | 0.37 | -0.097 |
P-value | Threshold |
---|---|
0.001 | 3.52151 |
0.0005 | 4.62046 |
0.0001 | 6.93647 |