MotifEGR3.H12RSNP.0.PSM.A
Gene (human)EGR3
(GeneCards)
Gene synonyms (human)PILOT
Gene (mouse)Egr3
Gene synonyms (mouse)Egr-3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusbRCGTGGGCGKdn
GC content70.42%
Information content (bits; total / per base)13.392 / 1.03
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words5943

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (5) 0.851 0.901 0.7 0.783 0.841 0.847 2.671 2.695 110.252 171.046

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.644 0.665 0.566 0.583 0.537 0.548
best 0.999 0.998 0.999 0.998 0.997 0.996
Methyl HT-SELEX, 1 experiments median 0.99 0.987 0.815 0.835 0.642 0.693
best 0.99 0.987 0.815 0.835 0.642 0.693
Non-Methyl HT-SELEX, 5 experiments median 0.616 0.634 0.555 0.567 0.533 0.539
best 0.999 0.998 0.999 0.998 0.997 0.996

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.847 0.491 0.846 0.519
batch 2 0.86 0.743 0.835 0.555
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyEGR {2.3.1.3} (TFClass)
TFClass IDTFClass: 2.3.1.3.3
HGNCHGNC:3240
MGIMGI:1306780
EntrezGene (human)GeneID:1960
(SSTAR profile)
EntrezGene (mouse)GeneID:13655
(SSTAR profile)
UniProt ID (human)EGR3_HUMAN
UniProt ID (mouse)EGR3_MOUSE
UniProt AC (human)Q06889
(TFClass)
UniProt AC (mouse)P43300
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
01872.751160.75908.753000.75
02852.25707.253634.25749.25
03379.04833.0417.0314.0
04244.085.05439.0175.0
05167.022.0971.04783.0
06247.07.05640.049.0
0720.019.05702.0202.0
0820.02.05885.036.0
09304.05306.0108.0225.0
10160.061.05595.0127.0
11302.0127.02020.03494.0
121858.75540.752163.751379.75
131542.75899.752151.751348.75
PFM
ACGT
010.1470.1950.1530.505
020.1430.1190.6120.126
030.0640.8130.070.053
040.0410.0140.9150.029
050.0280.0040.1630.805
060.0420.0010.9490.008
070.0030.0030.9590.034
080.0030.00.990.006
090.0510.8930.0180.038
100.0270.010.9410.021
110.0510.0210.340.588
120.3130.0910.3640.232
130.260.1510.3620.227
PWM
ACGT
01-0.531-0.246-0.4910.702
02-0.555-0.7410.894-0.683
03-1.3621.179-1.267-1.549
04-1.799-2.8371.297-2.128
05-2.174-4.12-0.4251.168
06-1.787-5.0891.333-3.37
07-4.206-4.2521.344-1.986
08-4.206-5.8771.375-3.663
09-1.5811.272-2.603-1.879
10-2.216-3.1591.325-2.444
11-1.588-2.4440.3070.854
120.224-1.0080.375-0.074
130.038-0.5010.37-0.097
Standard thresholds
P-value Threshold
0.001 3.52151
0.0005 4.62046
0.0001 6.93647