Motif | EGR3.H12INVIVO.0.PSM.A |
Gene (human) | EGR3 (GeneCards) |
Gene synonyms (human) | PILOT |
Gene (mouse) | Egr3 |
Gene synonyms (mouse) | Egr-3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | EGR3.H12INVIVO.0.PSM.A |
Gene (human) | EGR3 (GeneCards) |
Gene synonyms (human) | PILOT |
Gene (mouse) | Egr3 |
Gene synonyms (mouse) | Egr-3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 13 |
Consensus | nShGKGGGMGKvd |
GC content | 69.63% |
Information content (bits; total / per base) | 9.985 / 0.768 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 953 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (5) | 0.869 | 0.928 | 0.708 | 0.826 | 0.899 | 0.9 | 3.113 | 3.13 | 102.237 | 169.108 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.624 | 0.609 | 0.553 | 0.557 | 0.526 | 0.533 |
best | 0.947 | 0.894 | 0.948 | 0.901 | 0.934 | 0.89 | |
Methyl HT-SELEX, 1 experiments | median | 0.907 | 0.855 | 0.774 | 0.755 | 0.621 | 0.648 |
best | 0.907 | 0.855 | 0.774 | 0.755 | 0.621 | 0.648 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.601 | 0.584 | 0.543 | 0.544 | 0.522 | 0.525 |
best | 0.947 | 0.894 | 0.948 | 0.901 | 0.934 | 0.89 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.656 | 0.27 | 0.671 | 0.438 |
batch 2 | 0.669 | 0.364 | 0.725 | 0.435 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | C2H2 zinc finger factors {2.3} (TFClass) |
TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
TF subfamily | EGR {2.3.1.3} (TFClass) |
TFClass ID | TFClass: 2.3.1.3.3 |
HGNC | HGNC:3240 |
MGI | MGI:1306780 |
EntrezGene (human) | GeneID:1960 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13655 (SSTAR profile) |
UniProt ID (human) | EGR3_HUMAN |
UniProt ID (mouse) | EGR3_MOUSE |
UniProt AC (human) | Q06889 (TFClass) |
UniProt AC (mouse) | P43300 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 1 |
PCM | EGR3.H12INVIVO.0.PSM.A.pcm |
PWM | EGR3.H12INVIVO.0.PSM.A.pwm |
PFM | EGR3.H12INVIVO.0.PSM.A.pfm |
Alignment | EGR3.H12INVIVO.0.PSM.A.words.tsv |
Threshold to P-value map | EGR3.H12INVIVO.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | EGR3.H12INVIVO.0.PSM.A_jaspar_format.txt |
MEME format | EGR3.H12INVIVO.0.PSM.A_meme_format.meme |
Transfac format | EGR3.H12INVIVO.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 156.0 | 182.0 | 360.0 | 255.0 |
02 | 100.0 | 181.0 | 602.0 | 70.0 |
03 | 282.0 | 236.0 | 100.0 | 335.0 |
04 | 23.0 | 28.0 | 891.0 | 11.0 |
05 | 59.0 | 45.0 | 419.0 | 430.0 |
06 | 224.0 | 10.0 | 712.0 | 7.0 |
07 | 1.0 | 2.0 | 928.0 | 22.0 |
08 | 8.0 | 10.0 | 928.0 | 7.0 |
09 | 372.0 | 312.0 | 1.0 | 268.0 |
10 | 96.0 | 9.0 | 786.0 | 62.0 |
11 | 58.0 | 62.0 | 675.0 | 158.0 |
12 | 273.0 | 195.0 | 351.0 | 134.0 |
13 | 178.0 | 120.0 | 482.0 | 173.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.164 | 0.191 | 0.378 | 0.268 |
02 | 0.105 | 0.19 | 0.632 | 0.073 |
03 | 0.296 | 0.248 | 0.105 | 0.352 |
04 | 0.024 | 0.029 | 0.935 | 0.012 |
05 | 0.062 | 0.047 | 0.44 | 0.451 |
06 | 0.235 | 0.01 | 0.747 | 0.007 |
07 | 0.001 | 0.002 | 0.974 | 0.023 |
08 | 0.008 | 0.01 | 0.974 | 0.007 |
09 | 0.39 | 0.327 | 0.001 | 0.281 |
10 | 0.101 | 0.009 | 0.825 | 0.065 |
11 | 0.061 | 0.065 | 0.708 | 0.166 |
12 | 0.286 | 0.205 | 0.368 | 0.141 |
13 | 0.187 | 0.126 | 0.506 | 0.182 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.42 | -0.267 | 0.41 | 0.067 |
02 | -0.858 | -0.273 | 0.923 | -1.208 |
03 | 0.167 | -0.009 | -0.858 | 0.339 |
04 | -2.273 | -2.089 | 1.314 | -2.938 |
05 | -1.374 | -1.636 | 0.561 | 0.587 |
06 | -0.061 | -3.02 | 1.09 | -3.315 |
07 | -4.482 | -4.168 | 1.354 | -2.314 |
08 | -3.207 | -3.02 | 1.354 | -3.315 |
09 | 0.443 | 0.268 | -4.482 | 0.117 |
10 | -0.898 | -3.109 | 1.189 | -1.326 |
11 | -1.391 | -1.326 | 1.037 | -0.407 |
12 | 0.135 | -0.199 | 0.385 | -0.57 |
13 | -0.289 | -0.679 | 0.701 | -0.317 |
P-value | Threshold |
---|---|
0.001 | 4.77761 |
0.0005 | 5.65061 |
0.0001 | 7.36976 |