MotifE2F8.H12RSNP.0.P.D
Gene (human)E2F8
(GeneCards)
Gene synonyms (human)
Gene (mouse)E2f8
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length11
ConsensusdSGCGGGAAMn
GC content61.92%
Information content (bits; total / per base)11.979 / 1.089
Data sourcesChIP-Seq
Aligned words281

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.83 0.834 0.788 0.789 0.854 0.859 3.822 3.924 61.42 61.553

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.981 0.977 0.922 0.921
best 0.999 0.999 0.998 0.997 0.996 0.994
Methyl HT-SELEX, 1 experiments median 0.996 0.995 0.963 0.956 0.848 0.848
best 0.996 0.995 0.963 0.956 0.848 0.848
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.998 0.997 0.996 0.994
best 0.999 0.999 0.998 0.997 0.996 0.994
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyE2F {3.3.2} (TFClass)
TF subfamilyE2F {3.3.2.1} (TFClass)
TFClass IDTFClass: 3.3.2.1.8
HGNCHGNC:24727
MGIMGI:1922038
EntrezGene (human)GeneID:79733
(SSTAR profile)
EntrezGene (mouse)GeneID:108961
(SSTAR profile)
UniProt ID (human)E2F8_HUMAN
UniProt ID (mouse)E2F8_MOUSE
UniProt AC (human)A0AVK6
(TFClass)
UniProt AC (mouse)Q58FA4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
0145.026.058.0152.0
029.073.0195.04.0
032.08.0264.07.0
0417.0251.03.010.0
052.03.0252.024.0
063.017.0259.02.0
0712.016.0251.02.0
08274.01.03.03.0
09227.07.042.05.0
10187.036.032.026.0
1199.064.053.065.0
PFM
ACGT
010.160.0930.2060.541
020.0320.260.6940.014
030.0070.0280.940.025
040.060.8930.0110.036
050.0070.0110.8970.085
060.0110.060.9220.007
070.0430.0570.8930.007
080.9750.0040.0110.011
090.8080.0250.1490.018
100.6650.1280.1140.093
110.3520.2280.1890.231
PWM
ACGT
01-0.434-0.961-0.1870.761
02-1.9290.0381.008-2.584
03-3.045-2.031.309-2.143
04-1.3591.259-2.788-1.837
05-3.045-2.7881.263-1.037
06-2.788-1.3591.29-3.045
07-1.676-1.4151.259-3.045
081.346-3.392-2.788-2.788
091.159-2.143-0.501-2.414
100.967-0.65-0.763-0.961
110.337-0.091-0.275-0.076
Standard thresholds
P-value Threshold
0.001 4.30837
0.0005 5.259115
0.0001 7.19405