Motif | E2F8.H12RSNP.0.P.D |
Gene (human) | E2F8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | E2f8 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | D |
Motif | E2F8.H12RSNP.0.P.D |
Gene (human) | E2F8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | E2f8 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | D |
Motif length | 11 |
Consensus | dSGCGGGAAMn |
GC content | 61.92% |
Information content (bits; total / per base) | 11.979 / 1.089 |
Data sources | ChIP-Seq |
Aligned words | 281 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (7) | 0.83 | 0.834 | 0.788 | 0.789 | 0.854 | 0.859 | 3.822 | 3.924 | 61.42 | 61.553 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 0.998 | 0.997 | 0.981 | 0.977 | 0.922 | 0.921 |
best | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 | 0.994 | |
Methyl HT-SELEX, 1 experiments | median | 0.996 | 0.995 | 0.963 | 0.956 | 0.848 | 0.848 |
best | 0.996 | 0.995 | 0.963 | 0.956 | 0.848 | 0.848 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 | 0.994 |
best | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 | 0.994 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Fork head/winged helix factors {3.3} (TFClass) |
TF family | E2F {3.3.2} (TFClass) |
TF subfamily | E2F {3.3.2.1} (TFClass) |
TFClass ID | TFClass: 3.3.2.1.8 |
HGNC | HGNC:24727 |
MGI | MGI:1922038 |
EntrezGene (human) | GeneID:79733 (SSTAR profile) |
EntrezGene (mouse) | GeneID:108961 (SSTAR profile) |
UniProt ID (human) | E2F8_HUMAN |
UniProt ID (mouse) | E2F8_MOUSE |
UniProt AC (human) | A0AVK6 (TFClass) |
UniProt AC (mouse) | Q58FA4 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | E2F8.H12RSNP.0.P.D.pcm |
PWM | E2F8.H12RSNP.0.P.D.pwm |
PFM | E2F8.H12RSNP.0.P.D.pfm |
Alignment | E2F8.H12RSNP.0.P.D.words.tsv |
Threshold to P-value map | E2F8.H12RSNP.0.P.D.thr |
Motif in other formats | |
JASPAR format | E2F8.H12RSNP.0.P.D_jaspar_format.txt |
MEME format | E2F8.H12RSNP.0.P.D_meme_format.meme |
Transfac format | E2F8.H12RSNP.0.P.D_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 45.0 | 26.0 | 58.0 | 152.0 |
02 | 9.0 | 73.0 | 195.0 | 4.0 |
03 | 2.0 | 8.0 | 264.0 | 7.0 |
04 | 17.0 | 251.0 | 3.0 | 10.0 |
05 | 2.0 | 3.0 | 252.0 | 24.0 |
06 | 3.0 | 17.0 | 259.0 | 2.0 |
07 | 12.0 | 16.0 | 251.0 | 2.0 |
08 | 274.0 | 1.0 | 3.0 | 3.0 |
09 | 227.0 | 7.0 | 42.0 | 5.0 |
10 | 187.0 | 36.0 | 32.0 | 26.0 |
11 | 99.0 | 64.0 | 53.0 | 65.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.16 | 0.093 | 0.206 | 0.541 |
02 | 0.032 | 0.26 | 0.694 | 0.014 |
03 | 0.007 | 0.028 | 0.94 | 0.025 |
04 | 0.06 | 0.893 | 0.011 | 0.036 |
05 | 0.007 | 0.011 | 0.897 | 0.085 |
06 | 0.011 | 0.06 | 0.922 | 0.007 |
07 | 0.043 | 0.057 | 0.893 | 0.007 |
08 | 0.975 | 0.004 | 0.011 | 0.011 |
09 | 0.808 | 0.025 | 0.149 | 0.018 |
10 | 0.665 | 0.128 | 0.114 | 0.093 |
11 | 0.352 | 0.228 | 0.189 | 0.231 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.434 | -0.961 | -0.187 | 0.761 |
02 | -1.929 | 0.038 | 1.008 | -2.584 |
03 | -3.045 | -2.03 | 1.309 | -2.143 |
04 | -1.359 | 1.259 | -2.788 | -1.837 |
05 | -3.045 | -2.788 | 1.263 | -1.037 |
06 | -2.788 | -1.359 | 1.29 | -3.045 |
07 | -1.676 | -1.415 | 1.259 | -3.045 |
08 | 1.346 | -3.392 | -2.788 | -2.788 |
09 | 1.159 | -2.143 | -0.501 | -2.414 |
10 | 0.967 | -0.65 | -0.763 | -0.961 |
11 | 0.337 | -0.091 | -0.275 | -0.076 |
P-value | Threshold |
---|---|
0.001 | 4.30837 |
0.0005 | 5.259115 |
0.0001 | 7.19405 |