MotifE2F8.H12CORE.1.SM.B
Gene (human)E2F8
(GeneCards)
Gene synonyms (human)
Gene (mouse)E2f8
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusdKKRCGGGAAWhn
GC content51.52%
Information content (bits; total / per base)14.37 / 1.105
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9422

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.809 0.817 0.761 0.769 0.823 0.83 3.318 3.38 49.585 60.097

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.998 0.991 0.989 0.933 0.935
best 0.999 0.999 0.998 0.997 0.994 0.992
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.985 0.981 0.871 0.878
best 0.998 0.997 0.985 0.981 0.871 0.878
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.998 0.997 0.994 0.992
best 0.999 0.999 0.998 0.997 0.994 0.992
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyE2F {3.3.2} (TFClass)
TF subfamilyE2F {3.3.2.1} (TFClass)
TFClass IDTFClass: 3.3.2.1.8
HGNCHGNC:24727
MGIMGI:1922038
EntrezGene (human)GeneID:79733
(SSTAR profile)
EntrezGene (mouse)GeneID:108961
(SSTAR profile)
UniProt ID (human)E2F8_HUMAN
UniProt ID (mouse)E2F8_MOUSE
UniProt AC (human)A0AVK6
(TFClass)
UniProt AC (mouse)Q58FA4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013503.0998.01141.03780.0
021496.5642.51655.55627.5
03846.0628.05285.02663.0
042594.0119.06529.0180.0
058.09409.00.05.0
060.00.09422.00.0
071.024.09397.00.0
083.02.09416.01.0
099325.00.090.07.0
108710.041.0557.0114.0
116791.0601.0500.01530.0
123243.51464.51227.53486.5
132164.251943.252009.253305.25
PFM
ACGT
010.3720.1060.1210.401
020.1590.0680.1760.597
030.090.0670.5610.283
040.2750.0130.6930.019
050.0010.9990.00.001
060.00.01.00.0
070.00.0030.9970.0
080.00.00.9990.0
090.990.00.010.001
100.9240.0040.0590.012
110.7210.0640.0530.162
120.3440.1550.130.37
130.230.2060.2130.351
PWM
ACGT
010.397-0.857-0.7240.473
02-0.453-1.297-0.3520.87
03-1.022-1.3190.8080.123
040.096-2.9671.019-2.56
05-5.4351.384-6.938-5.779
06-6.938-6.9381.386-6.938
07-6.575-4.4961.383-6.938
08-6.1-6.311.385-6.575
091.375-6.938-3.241-5.537
101.307-3.998-1.439-3.009
111.058-1.363-1.546-0.431
120.32-0.475-0.6510.392
13-0.085-0.192-0.1590.338
Standard thresholds
P-value Threshold
0.001 1.57036
0.0005 3.224415
0.0001 6.731965