E2F7.H12RSNP.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F7.H12RSNP.1.P.D
Gene (human)	E2F7 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	12
Consensus	nKSGCGGGAARn
GC content	62.9%
Information content (bits; total / per base)	11.552 / 0.963
Data sources	ChIP-Seq
Aligned words	668

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.762	0.812	0.719	0.757	0.756	0.819	3.004	3.521	26.319	113.469

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.999	0.998
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.999	0.998

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.7
HGNC	HGNC:23820
MGI	MGI:1289147
EntrezGene (human)	GeneID:144455 (SSTAR profile)
EntrezGene (mouse)	GeneID:52679 (SSTAR profile)
UniProt ID (human)	E2F7_HUMAN
UniProt ID (mouse)	E2F7_MOUSE
UniProt AC (human)	Q96AV8 (TFClass)
UniProt AC (mouse)	Q6S7F2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	E2F7.H12RSNP.1.P.D.pcm
PWM	E2F7.H12RSNP.1.P.D.pwm
PFM	E2F7.H12RSNP.1.P.D.pfm
Alignment	E2F7.H12RSNP.1.P.D.words.tsv
Threshold to P-value map	E2F7.H12RSNP.1.P.D.thr
Motif in other formats
JASPAR format	E2F7.H12RSNP.1.P.D_jaspar_format.txt
MEME format	E2F7.H12RSNP.1.P.D_meme_format.meme
Transfac format	E2F7.H12RSNP.1.P.D_transfac_format.txt
Homer format	E2F7.H12RSNP.1.P.D_homer_format_0.001.txt E2F7.H12RSNP.1.P.D_homer_format_0.0005.txt E2F7.H12RSNP.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	113.0	136.0	202.0	217.0
02	71.0	48.0	173.0	376.0
03	18.0	141.0	494.0	15.0
04	10.0	24.0	625.0	9.0
05	53.0	590.0	7.0	18.0
06	29.0	8.0	593.0	38.0
07	6.0	69.0	580.0	13.0
08	8.0	33.0	622.0	5.0
09	611.0	8.0	33.0	16.0
10	527.0	13.0	115.0	13.0
11	391.0	91.0	144.0	42.0
12	254.0	128.0	165.0	121.0

PFM

	A	C	G	T
01	0.169	0.204	0.302	0.325
02	0.106	0.072	0.259	0.563
03	0.027	0.211	0.74	0.022
04	0.015	0.036	0.936	0.013
05	0.079	0.883	0.01	0.027
06	0.043	0.012	0.888	0.057
07	0.009	0.103	0.868	0.019
08	0.012	0.049	0.931	0.007
09	0.915	0.012	0.049	0.024
10	0.789	0.019	0.172	0.019
11	0.585	0.136	0.216	0.063
12	0.38	0.192	0.247	0.181

PWM

	A	C	G	T
01	-0.386	-0.203	0.189	0.26
02	-0.842	-1.223	0.035	0.806
03	-2.151	-0.167	1.078	-2.317
04	-2.674	-1.884	1.313	-2.764
05	-1.127	1.255	-2.973	-2.151
06	-1.706	-2.863	1.26	-1.448
07	-3.096	-0.87	1.238	-2.445
08	-2.863	-1.583	1.308	-3.237
09	1.29	-2.863	-1.583	-2.258
10	1.143	-2.445	-0.369	-2.445
11	0.845	-0.599	-0.147	-1.352
12	0.416	-0.263	-0.012	-0.319

Standard thresholds

P-value	Threshold
0.001	4.32901
0.0005	5.25419
0.0001	7.17831