E2F7.H12RSNP.0.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F7.H12RSNP.0.S.D
Gene (human)	E2F7 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	16
Consensus	dWTTTGGCGGGAAWdn
GC content	46.88%
Information content (bits; total / per base)	21.41 / 1.338
Data sources	HT-SELEX
Aligned words	9238

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.785	0.833	0.741	0.777	0.717	0.78	2.777	3.289	29.62	104.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.995	0.995
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.995	0.995

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.7
HGNC	HGNC:23820
MGI	MGI:1289147
EntrezGene (human)	GeneID:144455 (SSTAR profile)
EntrezGene (mouse)	GeneID:52679 (SSTAR profile)
UniProt ID (human)	E2F7_HUMAN
UniProt ID (mouse)	E2F7_MOUSE
UniProt AC (human)	Q96AV8 (TFClass)
UniProt AC (mouse)	Q6S7F2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	E2F7.H12RSNP.0.S.D.pcm
PWM	E2F7.H12RSNP.0.S.D.pwm
PFM	E2F7.H12RSNP.0.S.D.pfm
Alignment	E2F7.H12RSNP.0.S.D.words.tsv
Threshold to P-value map	E2F7.H12RSNP.0.S.D.thr
Motif in other formats
JASPAR format	E2F7.H12RSNP.0.S.D_jaspar_format.txt
MEME format	E2F7.H12RSNP.0.S.D_meme_format.meme
Transfac format	E2F7.H12RSNP.0.S.D_transfac_format.txt
Homer format	E2F7.H12RSNP.0.S.D_homer_format_0.001.txt E2F7.H12RSNP.0.S.D_homer_format_0.0005.txt E2F7.H12RSNP.0.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3071.25	924.25	2889.25	2353.25
02	3348.5	222.5	557.5	5109.5
03	1228.0	190.0	459.0	7361.0
04	365.0	128.0	110.0	8635.0
05	63.0	7.0	30.0	9138.0
06	5.0	281.0	8951.0	1.0
07	0.0	9.0	9229.0	0.0
08	0.0	9238.0	0.0	0.0
09	0.0	0.0	9238.0	0.0
10	0.0	52.0	9186.0	0.0
11	3.0	27.0	9208.0	0.0
12	9210.0	1.0	14.0	13.0
13	8659.0	20.0	501.0	58.0
14	6478.0	676.0	507.0	1577.0
15	2642.25	1280.25	1600.25	3715.25
16	1802.75	1628.75	2130.75	3675.75

PFM

	A	C	G	T
01	0.332	0.1	0.313	0.255
02	0.362	0.024	0.06	0.553
03	0.133	0.021	0.05	0.797
04	0.04	0.014	0.012	0.935
05	0.007	0.001	0.003	0.989
06	0.001	0.03	0.969	0.0
07	0.0	0.001	0.999	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.006	0.994	0.0
11	0.0	0.003	0.997	0.0
12	0.997	0.0	0.002	0.001
13	0.937	0.002	0.054	0.006
14	0.701	0.073	0.055	0.171
15	0.286	0.139	0.173	0.402
16	0.195	0.176	0.231	0.398

PWM

	A	C	G	T
01	0.285	-0.914	0.224	0.019
02	0.371	-2.331	-1.418	0.794
03	-0.631	-2.487	-1.612	1.158
04	-1.84	-2.876	-3.025	1.318
05	-3.567	-5.518	-4.271	1.375
06	-5.76	-2.099	1.354	-6.557
07	-6.92	-5.322	1.385	-6.92
08	-6.92	1.386	-6.92	-6.92
09	-6.92	-6.92	1.386	-6.92
10	-6.92	-3.752	1.38	-6.92
11	-6.081	-4.369	1.382	-6.92
12	1.383	-6.557	-4.956	-5.019
13	1.321	-4.642	-1.525	-3.647
14	1.031	-1.226	-1.513	-0.381
15	0.134	-0.589	-0.366	0.475
16	-0.247	-0.349	-0.08	0.464

Standard thresholds

P-value	Threshold
0.001	-5.12009
0.0005	-3.00544
0.0001	1.44401